Chimeric Animal Inflammation Prevention Technology

Publication ID: 24-11856927_0001_PTD
Published: October 27, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Chimeric Animal Inflammation Prevention Technology,” Published Technical Disclosure No. 24-11856927_0001_PTD, Published October 27, 2025, available at https://archive.pr1or.art/24-11856927_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,927.

Background and Problem Solved

The original patent disclosed a method for obtaining an adult individual from a xenogeneic or allogeneic chimeric animal fetus individual, but it had limitations in addressing immune response and inflammation after birth. The present invention addresses these limitations by introducing a monitoring module, controlled release composition, and sensor-enabled device to prevent and treat inflammation in chimeric animals more effectively.

Novelty and Inventive Step

The present invention introduces novel elements, such as the monitoring module, controlled release composition, and sensor-enabled device, which are not present in the original patent. These elements provide an inventive step by enabling more efficient, safer, and targeted treatment of inflammation in chimeric animals.

Alternative Embodiments and Variations

Alternative embodiments of the invention could include varying the type of anti-inflammatory agent or immunosuppressive agent used, adjusting the controlled release mechanism, or integrating the system with other medical devices. Variations could also involve adapting the invention for use in different species or for treating different types of inflammation.

Potential Commercial Applications and Market

The invention has significant commercial potential in the fields of regenerative medicine, biotechnology, and veterinary care. It could be used to improve the health and well-being of chimeric animals, enabling the development of new therapies and treatments. The target market includes research institutions, biotech companies, and veterinary clinics.

CPC Classifications

SectionClassGroup
A A01 A01K67/0271
A A61 A61K31/573
A A61 A61P37/06
A A01 A01K2217/05
A A01 A01K2217/075
A A01 A01K2227/105
A A01 A01K2267/035
C C12 C12N15/09

Original Patent Information

Patent NumberUS 11,856,927
TitleFinding and treatment of inflammation after birth in chimeric animal
Assignee(s)The University of Tokyo