Chimeric Animal Inflammation Treatment Innovation
Legal Citation
Background and Problem Solved
The original patent disclosed methods for treating and preventing immune response and inflammation in chimeric animals after birth. However, these methods were not tailored to specific, narrow markets or unique operational environments. The present invention addresses this limitation by providing specialized variations and niche solutions for treating inflammation in chimeric animals after birth, thereby expanding the applicability of the original invention.
Novelty and Inventive Step
The novelty of the present invention lies in the adaptation of the original patent's methods for treating and preventing immune response and inflammation in chimeric animals after birth to specialized environments, such as high-security needs, disaster relief, or extreme weather conditions. The inventive step is the recognition of the need for tailored solutions for these specific markets and the development of compositions and methods that address these needs.
Alternative Embodiments and Variations
Alternative embodiments of the present invention include the use of different anti-inflammatory agents or immunosuppressive agents, or the administration of these agents through different routes or at different stages of the chimeric animal's development. Variations of the invention may also include the use of different types of xenogeneic or allogeneic cells, or the development of new tolerance-inducing agents.
Potential Commercial Applications and Market
The present invention has significant commercial potential in the fields of biotechnology, veterinary medicine, and disaster relief. The invention's ability to provide specialized solutions for treating inflammation in chimeric animals after birth in high-security environments, disaster relief scenarios, or extreme weather conditions addresses a significant unmet need in these markets.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01K67/0271 |
| A | A61 | A61K31/573 |
| A | A61 | A61P37/06 |
| A | A01 | A01K2217/05 |
| A | A01 | A01K2217/075 |
| A | A01 | A01K2227/105 |
| A | A01 | A01K2267/035 |
| C | C12 | C12N15/09 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Veterinary biotechnology and immunological research, specifically focused on chimeric animal development, stem cell transplantation, and immune system modulation
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in veterinary medicine, immunology, or biotechnology, possessing expertise in stem cell manipulation, immunosuppressive techniques, and chimeric animal research methodologies
Obviousness Rationale
A PHOSITA would recognize that the source patent's core method of managing inflammation in chimeric animals after birth provides a foundational framework that can be readily adapted to specific environmental contexts. The PTD's variations represent predictable extensions of the original patent's core principles, applying known immunosuppressive and anti-inflammatory strategies to specialized scenarios. The technical approach of administering agents to prevent or manage immune responses remains fundamentally consistent across the disclosed variations.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,856,927 |
|---|---|
| Title | Finding and treatment of inflammation after birth in chimeric animal |
| Assignee(s) | The University of Tokyo |