Chimeric Animal Inflammation Treatment Innovation

Publication ID: 24-11856927_0004_PTD
Published: October 26, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Chimeric Animal Inflammation Treatment Innovation,” Published Technical Disclosure No. 24-11856927_0004_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856927_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,927.

Background and Problem Solved

The original patent disclosed methods for treating and preventing immune response and inflammation in chimeric animals after birth. However, these methods were not tailored to specific, narrow markets or unique operational environments. The present invention addresses this limitation by providing specialized variations and niche solutions for treating inflammation in chimeric animals after birth, thereby expanding the applicability of the original invention.

Novelty and Inventive Step

The novelty of the present invention lies in the adaptation of the original patent's methods for treating and preventing immune response and inflammation in chimeric animals after birth to specialized environments, such as high-security needs, disaster relief, or extreme weather conditions. The inventive step is the recognition of the need for tailored solutions for these specific markets and the development of compositions and methods that address these needs.

Alternative Embodiments and Variations

Alternative embodiments of the present invention include the use of different anti-inflammatory agents or immunosuppressive agents, or the administration of these agents through different routes or at different stages of the chimeric animal's development. Variations of the invention may also include the use of different types of xenogeneic or allogeneic cells, or the development of new tolerance-inducing agents.

Potential Commercial Applications and Market

The present invention has significant commercial potential in the fields of biotechnology, veterinary medicine, and disaster relief. The invention's ability to provide specialized solutions for treating inflammation in chimeric animals after birth in high-security environments, disaster relief scenarios, or extreme weather conditions addresses a significant unmet need in these markets.

CPC Classifications

SectionClassGroup
A A01 A01K67/0271
A A61 A61K31/573
A A61 A61P37/06
A A01 A01K2217/05
A A01 A01K2217/075
A A01 A01K2227/105
A A01 A01K2267/035
C C12 C12N15/09

Original Patent Information

Patent NumberUS 11,856,927
TitleFinding and treatment of inflammation after birth in chimeric animal
Assignee(s)The University of Tokyo