Chimeric Animal Inflammation Treatment Method
Legal Citation
Background and Problem Solved
The original patent disclosed a method for obtaining an adult individual from a xenogeneic or allogeneic chimeric animal fetus individual. However, the patent did not fully address the issue of inflammation after birth, which can lead to immune response and rejection of the chimeric cells. The present invention solves this problem by introducing a system and method for monitoring and treating inflammation in chimeric animals after birth, thereby improving their survival rate.
Novelty and Inventive Step
The present invention introduces a novel system and method for reducing inflammation in chimeric animals after birth, which is not addressed in the original patent. The inventive step lies in the combination of a monitoring unit and a treatment unit, as well as the composition and method for enhancing tolerance to allogeneic or xenogeneic cells.
Alternative Embodiments and Variations
Alternative embodiments of the invention include using different types of anti-inflammatory agents or immunosuppressive agents, varying the timing and dosage of administration, and incorporating additional components to the system and composition. Variations of the method for enhancing tolerance may include using different tolerance-inducing agents or adjusting the timing of administration.
Potential Commercial Applications and Market
The present invention has significant commercial potential in the field of regenerative medicine, particularly in the development of chimeric animal models for human disease research and therapy. The invention may also have applications in the veterinary industry for improving the health and survival rate of chimeric animals.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01K67/0271 |
| A | A61 | A61K31/573 |
| A | A61 | A61P37/06 |
| A | A01 | A01K2217/05 |
| A | A01 | A01K2217/075 |
| A | A01 | A01K2227/105 |
| A | A01 | A01K2267/035 |
| C | C12 | C12N15/09 |
Original Patent Information
| Patent Number | US 11,856,927 |
|---|---|
| Title | Finding and treatment of inflammation after birth in chimeric animal |
| Assignee(s) | The University of Tokyo |