Chimeric Animal Immune Response Innovation
Legal Citation
Background and Problem Solved
The original patent disclosed methods for obtaining adult individuals from xenogeneic or allogeneic chimeric animal fetuses, but it did not address the specific challenges of immune response and inflammation in unique operational environments. The present invention fills this gap by providing specialized solutions for high-security research, disaster relief, and extreme weather conditions.
Novelty and Inventive Step
The new claims provide a novel and non-obvious solution by adapting the original patent's methods and compositions for specialized applications in high-security facilities, disaster relief scenarios, and extreme weather conditions. The inventive step lies in the recognition of the need for tailored solutions for these unique environments and the development of specific formulations, systems, and methods to address them.
Alternative Embodiments and Variations
Alternative embodiments of the invention could include the use of different types of chimeric animals, such as those with genetic modifications or induced pluripotent stem cells. Variations of the composition and system could include different formulations of the anti-inflammatory agent or immunosuppressive agent, or the use of additional components to enhance their efficacy. Other operational environments, such as space exploration or high-altitude research, could also be targeted by adapting the invention's components and methods.
Potential Commercial Applications and Market
The invention has significant commercial potential in the fields of biotechnology, pharmaceuticals, and life sciences. The high-security research market, disaster relief industry, and extreme weather condition applications could benefit from the invention's specialized solutions. Additionally, the invention could have implications for human health and disease research, as well as veterinary medicine.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01K67/0271 |
| A | A61 | A61K31/573 |
| A | A61 | A61P37/06 |
| A | A01 | A01K2217/05 |
| A | A01 | A01K2217/075 |
| A | A01 | A01K2227/105 |
| A | A01 | A01K2267/035 |
| C | C12 | C12N15/09 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Veterinary biotechnology and immunological research, focusing on chimeric animal models, stem cell manipulation, and immunological intervention techniques
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in veterinary science or molecular biology, experienced in stem cell techniques, animal model development, and immunological intervention strategies, familiar with genetic chimera creation and immunosuppressive protocols
Obviousness Rationale
A person skilled in the art would recognize that the PTD's variations represent predictable extensions of the source patent's core methodology by applying the established chimeric animal inflammation management technique to specialized environmental contexts. The fundamental scientific principles of immune response modulation and chimeric animal development remain consistent across the disclosed scenarios. The PTD's claims represent logical adaptations of the original patent's core technological framework to novel operational environments.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,856,927 |
|---|---|
| Title | Finding and treatment of inflammation after birth in chimeric animal |
| Assignee(s) | The University of Tokyo |