Chimeric Animal Immune Response Innovation

Publication ID: 24-11856927_0009_PTD
Published: October 26, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Chimeric Animal Immune Response Innovation,” Published Technical Disclosure No. 24-11856927_0009_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856927_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,927.

Background and Problem Solved

The original patent disclosed methods for obtaining adult individuals from xenogeneic or allogeneic chimeric animal fetuses, but it did not address the specific challenges of immune response and inflammation in unique operational environments. The present invention fills this gap by providing specialized solutions for high-security research, disaster relief, and extreme weather conditions.

Novelty and Inventive Step

The new claims provide a novel and non-obvious solution by adapting the original patent's methods and compositions for specialized applications in high-security facilities, disaster relief scenarios, and extreme weather conditions. The inventive step lies in the recognition of the need for tailored solutions for these unique environments and the development of specific formulations, systems, and methods to address them.

Alternative Embodiments and Variations

Alternative embodiments of the invention could include the use of different types of chimeric animals, such as those with genetic modifications or induced pluripotent stem cells. Variations of the composition and system could include different formulations of the anti-inflammatory agent or immunosuppressive agent, or the use of additional components to enhance their efficacy. Other operational environments, such as space exploration or high-altitude research, could also be targeted by adapting the invention's components and methods.

Potential Commercial Applications and Market

The invention has significant commercial potential in the fields of biotechnology, pharmaceuticals, and life sciences. The high-security research market, disaster relief industry, and extreme weather condition applications could benefit from the invention's specialized solutions. Additionally, the invention could have implications for human health and disease research, as well as veterinary medicine.

CPC Classifications

SectionClassGroup
A A01 A01K67/0271
A A61 A61K31/573
A A61 A61P37/06
A A01 A01K2217/05
A A01 A01K2217/075
A A01 A01K2227/105
A A01 A01K2267/035
C C12 C12N15/09

Original Patent Information

Patent NumberUS 11,856,927
TitleFinding and treatment of inflammation after birth in chimeric animal
Assignee(s)The University of Tokyo