Advanced Lung Preservation Solution for Organ Transplant
Legal Citation
Background and Problem Solved
Current organ preservation techniques, such as hypothermic storage, have limitations in maintaining optimal lung function and viability. The original patent addressed these limitations with a perfusion solution for ex-vivo organ care. However, there remains a need for further improvements to enhance lung preservation and functionality. The present invention addresses these limitations by introducing novel perfusion solution compositions, optimized perfusion conditions, and advanced monitoring systems.
Novelty and Inventive Step
The present invention introduces novel and non-obvious improvements over the original patent, including the optimized perfusion solution composition, advanced monitoring systems, and optimized perfusion conditions. These improvements enhance lung viability and functionality, providing a significant advancement in the field of ex-vivo organ care.
Alternative Embodiments and Variations
Alternative embodiments of the invention could include varying the perfusion solution composition, adjusting the temperature range, or modifying the monitoring system to accommodate different types of organs or perfusion protocols. Additionally, the invention could be adapted for use in other areas of organ care, such as kidney or liver preservation.
Potential Commercial Applications and Market
The enhanced organ care solution has significant commercial potential in the field of organ transplantation, particularly in the preservation and transportation of donor lungs. The invention could be marketed to organ procurement organizations, hospitals, and research institutions, providing a valuable tool for improving lung viability and functionality.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01N1/0226 |
| A | A01 | A01N1/0247 |
Original Patent Information
| Patent Number | US 11,856,944 |
|---|---|
| Title | Organ care solution for ex-vivo machine perfusion of donor lungs |
| Assignee(s) | TRANSMEDICS, INC. |