Advanced Organ Preservation: Machine Perfusion Tech

Publication ID: 24-11856944_0002_PTD
Published: October 26, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Advanced Organ Preservation: Machine Perfusion Tech,” Published Technical Disclosure No. 24-11856944_0002_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856944_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,944.

Background and Problem Solved

Current organ preservation techniques are limited to hypothermic storage, which can lead to organ damage and reduced viability. The original patent addressed this limitation for lungs, but other organs still rely on outdated preservation methods. This invention solves this problem by adapting the machine perfusion technology to support the preservation of multiple organs.

Novelty and Inventive Step

The new claims introduce a novel application of the original patent's technology to multiple organs, demonstrating an inventive step in the field of organ preservation. The adaptation of the perfusion solution and organ care system to accommodate various organs constitutes a non-obvious extension of the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different perfusion solutions, tailored to specific organs or disease conditions. Variations may include the integration of additional components, such as sensors or monitoring systems, to enhance the organ care system's functionality.

Potential Commercial Applications and Market

The invention has significant commercial potential in the organ transplantation market, enabling the preservation and transportation of multiple organs for transplantation. The target industries include organ procurement organizations, transplantation centers, and pharmaceutical companies involved in organ preservation solutions.

CPC Classifications

SectionClassGroup
A A01 A01N1/0226
A A01 A01N1/0247

Original Patent Information

Patent NumberUS 11,856,944
TitleOrgan care solution for ex-vivo machine perfusion of donor lungs
Assignee(s)TRANSMEDICS, INC.