Advanced Lung Preservation Tech for Organ Transplantation

Publication ID: 24-11856944_0004_PTD
Published: October 26, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Advanced Lung Preservation Tech for Organ Transplantation,” Published Technical Disclosure No. 24-11856944_0004_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856944_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,944.

Background and Problem Solved

Current organ preservation techniques are limited in their ability to adapt to diverse environmental conditions, resulting in suboptimal lung function and reduced transplant success rates. This invention addresses these limitations by providing specialized organ care solutions tailored to specific operational environments, ensuring optimal lung function and improved transplant outcomes.

Novelty and Inventive Step

The invention's novelty lies in its specialized solutions for extreme environments, which depart from the traditional one-size-fits-all approach to organ care. The inventive step resides in the tailored design of perfusion liquids and OCS configurations, which address the specific challenges of each environment and provide improved lung function and transplant outcomes.

Alternative Embodiments and Variations

Alternative embodiments of the invention may include additional specialized solutions for other extreme environments, such as tropical or desert settings. Variations may also include modifications to the perfusion liquids and OCS configurations to accommodate different types of organs or specific medical conditions.

Potential Commercial Applications and Market

The invention has significant commercial potential in the organ transplantation industry, particularly in regions prone to natural disasters, high-altitude areas, or areas with extreme weather conditions. The specialized solutions may also appeal to military and government agencies, as well as organizations involved in disaster relief and humanitarian efforts.

CPC Classifications

SectionClassGroup
A A01 A01N1/0226
A A01 A01N1/0247

Original Patent Information

Patent NumberUS 11,856,944
TitleOrgan care solution for ex-vivo machine perfusion of donor lungs
Assignee(s)TRANSMEDICS, INC.