AI-Enhanced Ex-Vivo Lung Perfusion System Innovation

Publication ID: 24-11856944_0005_PTD
Published: October 26, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “AI-Enhanced Ex-Vivo Lung Perfusion System Innovation,” Published Technical Disclosure No. 24-11856944_0005_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856944_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,944.

Background and Problem Solved

Current organ preservation techniques, as described in the original patent, are limited by their reliance on hypothermic storage and chemical perfusion solutions. The present invention addresses these limitations by introducing a paradigm shift in ex-vivo lung perfusion, enabling real-time adaptation to changing lung conditions, predictive analytics, and decentralized data tracking.

Novelty and Inventive Step

The present invention's novelty lies in the integration of artificial intelligence, machine learning, and bio-inspired materials to create a real-time adaptive ex-vivo lung perfusion system. The inventive step is the use of these technologies to overcome the limitations of current organ preservation techniques, enabling a paradigm shift in the field.

Alternative Embodiments and Variations

Alternative embodiments of the invention may include the use of different machine learning algorithms, varying types of bio-inspired materials, or alternative decentralized data tracking platforms. Variations of the invention could also include the application of these technologies to other organs or tissues, expanding the scope of the invention beyond lung perfusion.

Potential Commercial Applications and Market

The intelligent ex-vivo lung perfusion system has significant commercial potential in the organ transplantation and regenerative medicine industries, with potential applications in hospitals, research institutions, and biotechnology companies. The market for this technology is expected to grow as the demand for organ transplantation increases, driven by the rising need for effective organ preservation solutions.

CPC Classifications

SectionClassGroup
A A01 A01N1/0226
A A01 A01N1/0247

Original Patent Information

Patent NumberUS 11,856,944
TitleOrgan care solution for ex-vivo machine perfusion of donor lungs
Assignee(s)TRANSMEDICS, INC.