Advanced Lung Preservation Solution for Organ Transplant
Legal Citation
Background and Problem Solved
Current organ preservation techniques, such as those described in the original patent, have limitations including oxidative stress, inefficient perfusion, and inadequate oxygenation. This invention addresses these limitations by introducing novel components and adjustments to the perfusion solution and system, enabling more efficient and effective ex-vivo lung perfusion.
Novelty and Inventive Step
The invention's novelty lies in the combination of novel antioxidant components, real-time perfusion liquid adjustments, modified colloid components, and advanced gas exchange modules, which collectively provide a significant improvement over the original patent. The inventive step is the integration of these components to create a more efficient, effective, and viable ex-vivo lung perfusion system.
Alternative Embodiments and Variations
Alternative embodiments may include variations in the antioxidant component, colloid composition, or gas exchange module design. Additionally, the system could be adapted for perfusion of other organs, such as the heart or liver, or integrated with other organ preservation technologies.
Potential Commercial Applications and Market
The enhanced organ care solution has significant commercial potential in the organ transplantation market, addressing the need for improved lung preservation and transplantation outcomes. The invention could be marketed to organ procurement organizations, transplantation centers, and pharmaceutical companies, with potential applications in human transplantation and potentially in veterinary medicine.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01N1/0226 |
| A | A01 | A01N1/0247 |
Original Patent Information
| Patent Number | US 11,856,944 |
|---|---|
| Title | Organ care solution for ex-vivo machine perfusion of donor lungs |
| Assignee(s) | TRANSMEDICS, INC. |