Revolutionary Multi-Industry Organ Preservation Tech

Publication ID: 24-11856944_0007_PTD
Published: October 26, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Revolutionary Multi-Industry Organ Preservation Tech,” Published Technical Disclosure No. 24-11856944_0007_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856944_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,944.

Background and Problem Solved

Current methods in these fields often rely on inadequate solutions, leading to inefficiencies, environmental degradation, and loss of life. The original organ care solution, designed for ex-vivo machine perfusion of donor lungs, demonstrated the effectiveness of a perfusion solution in maintaining organ health. This invention adapts and expands this technology to address critical challenges in various industries.

Novelty and Inventive Step

The novelty of this invention lies in the adaptation of the original organ care solution to entirely new fields, demonstrating the versatility and broad applicability of the core technology. The inventive step resides in the recognition of the potential for this technology to address pressing global challenges, and the development of innovative solutions to realize this potential.

Alternative Embodiments and Variations

Alternative embodiments may include variations in sensor networks, database structures, and machine learning algorithms for agricultural water management. Other variations may involve different perfusion solution compositions, tailored to specific plant or coral species, or modular designs for urban green space revitalization. Furthermore, the invention could be adapted for use in other industries, such as environmental remediation or biotechnology research.

Potential Commercial Applications and Market

This invention has significant commercial potential in various industries, including agriculture, urban planning, environmental conservation, disaster response, and food security. The market for these applications is substantial, with potential customers including government agencies, private companies, and non-profit organizations. The invention's adaptability and versatility make it an attractive solution for a wide range of industries and use cases.

CPC Classifications

SectionClassGroup
A A01 A01N1/0226
A A01 A01N1/0247

Field of Art

Biomedical engineering and organ preservation technologies, with expertise in ex-vivo perfusion systems, solution chemistry, and organ maintenance techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical researcher with advanced degrees in bioengineering, biochemistry, or medical sciences, possessing knowledge of organ preservation techniques, perfusion solution composition, and interdisciplinary technology adaptation

Obviousness Rationale

A PHOSITA would recognize the fundamental principles of ex-vivo perfusion as universally applicable across biological systems, understanding that the core technology of maintaining living tissue through carefully composed nutrient solutions can be systematically adapted to different contexts. The source patent's detailed perfusion solution methodology provides a transferable framework for preserving biological materials beyond organ transplantation. The disclosed variations represent predictable extensions of known preservation techniques by applying established ex-vivo care principles to alternative domains.

Obvious Combinations & Variations

Source Patent Element
Perfusion solution containing nutrients, colloids, buffers, and specific chemical compounds for maintaining organ viability
PTD Variation
Adapting perfusion solution for plant seed germination and agricultural water management
Obviousness Reasoning
A PHOSITA would recognize that nutrient composition and preservation techniques are fundamentally transferable across biological systems, with predictable modifications based on specific tissue requirements
Source Patent Element
Temperature-controlled ex-vivo organ maintenance system
PTD Variation
Submerged, temperature-controlled chamber for coral reef preservation
Obviousness Reasoning
The core technological principles of maintaining biological tissue under controlled conditions are directly applicable across different living systems, representing a known technique for systematic technology transfer
Source Patent Element
Machine perfusion methodology for maintaining biological tissue viability
PTD Variation
Mobile self-contained unit for emergency organ preservation and disaster response
Obviousness Reasoning
Extending preservation technologies to emergency contexts represents a predictable solution using known perfusion system design principles, with minimal inventive complexity
Source Patent Element
Chemical perfusion solution with specific nutrient and molecular composition
PTD Variation
Urban green space plant care using tailored perfusion solutions
Obviousness Reasoning
Modifying perfusion solution composition for different biological contexts is a routine design choice for a PHOSITA, representing a predictable engineering adaptation
35 U.S.C. § 103 Summary: Based on US Patent 11856944's comprehensive disclosure of ex-vivo perfusion technologies, a person having ordinary skill in the art would find the variations disclosed herein obvious and anticipated, as they represent systematic extensions of known preservation techniques through predictable combinations of established technological principles. The source patent's detailed methodology provides sufficient teaching and motivation for adapting perfusion technologies across diverse biological preservation contexts, rendering subsequent claims obvious under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,856,944
TitleOrgan care solution for ex-vivo machine perfusion of donor lungs
Assignee(s)TRANSMEDICS, INC.