Advanced Lung Perfusion for Extreme Environments
Legal Citation
Background and Problem Solved
Current ex-vivo lung perfusion solutions are limited in their ability to operate effectively in non-standard environments. The original patent disclosed a perfusion solution for machine perfusion of donor lungs at physiologic or near-physiologic conditions. However, these solutions are not optimized for unique operational environments, such as high-altitude, disaster relief, high-security, extreme cold, and remote areas. This invention addresses these limitations by providing specialized solutions that can maintain a lung at or near normal physiologic conditions in these niche environments.
Novelty and Inventive Step
The new claims provide a novel and non-obvious solution by adapting the original perfusion solution for specific, niche operational environments. The inventive step lies in the modification of the solution's composition and packaging to accommodate the unique challenges of each environment.
Alternative Embodiments and Variations
Alternative embodiments of the invention could include additional specialized solutions for other niche environments, such as tropical or desert environments. Variations could also include different packaging options or modifications to the solution's composition to accommodate specific environmental factors.
Potential Commercial Applications and Market
The invention has significant commercial potential in the organ transplantation and disaster relief industries, particularly in regions with unique environmental challenges. The specialized solutions could be marketed to hospitals, research institutions, and disaster relief organizations operating in these environments.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01N1/0226 |
| A | A01 | A01N1/0247 |
Original Patent Information
| Patent Number | US 11,856,944 |
|---|---|
| Title | Organ care solution for ex-vivo machine perfusion of donor lungs |
| Assignee(s) | TRANSMEDICS, INC. |