AI-Enhanced Lung Preservation System: Machine Perfusion Tech

Current organ preservation techniques are limited by hypothermic storage and lack of real-time monitoring, leading to suboptimal lung function and viability. The original patent addressed this by introducing a perfusion solution for machine perfusion of donor lungs at physiologic conditions. However, this approach has limitations in terms of adaptability, customization, and real-time feedback. The present invention overcomes these limitations by introducing a system that integrates machine perfusion with bio-artificial interfaces, AI-driven optimization, and personalized perfusion solutions.

The invention's novelty lies in the integration of machine perfusion with bio-artificial interfaces and AI-driven optimization, enabling real-time monitoring and adaptation to changing lung conditions. The inventive step is the use of AI-driven optimization to predict and prevent potential lung damage, and to tailor the perfusion solution and machine perfusion parameters to the specific lung's metabolic needs.

Alternative embodiments of the invention include the use of different bio-artificial interfaces, such as microfluidic channels or nanotechnology-based sensors. Variations of the invention could also include the integration of stem cells or other therapeutic agents to enhance lung viability and function.

The invention has significant commercial potential in the field of lung transplantation, with potential applications in organ preservation, transportation, and transplantation. The target market includes hospitals, research institutions, and biotechnology companies involved in lung transplantation and regenerative medicine.