Advanced MOF Biospecimen Preservation Technology
Legal Citation
Background and Problem Solved
The original patent disclosed methods and systems for preparing and preserving biological samples using metal-organic framework (MOF) encapsulants. However, the existing technology has inherent limitations, including poor thermal stability and lack of control over biomarker preservation. The present invention addresses these limitations by introducing novel MOF encapsulants with improved thermal stability, nanoporous materials with controlled release mechanisms, and integrated temperature monitoring and control systems.
Novelty and Inventive Step
The present invention's novelty lies in the introduction of improved thermal stability, controlled release mechanisms, and customized preservation conditions, which overcome the limitations of the original patent. The inventive step is the combination of these features, which provides a significant advancement in the field of biological sample preservation.
Alternative Embodiments and Variations
Alternative embodiments of the invention include the use of different MOF materials, varying the nanoporous structure, and incorporating additional features such as humidity control and biomarker detection. Variations of the invention may also include different substrates, such as glass or plastic, and alternative desiccant materials.
Potential Commercial Applications and Market
The present invention has significant commercial potential in the biomedical research and clinical diagnosis industries, where high-quality biospecimens are critical. The invention's ability to provide enhanced preservation conditions and controlled release mechanisms can improve the accuracy and reliability of biomarker analysis, leading to better disease diagnosis and treatment outcomes.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01N1/0231 |
| G | G01 | G01N1/4044 |
Original Patent Information
| Patent Number | US 11,856,945 |
|---|---|
| Title | Methods and systems for preparing and preserving a biological sample |
| Assignee(s) | Washington University |