MOF Biomarker Preservation: Multi-Industry Innovation

Publication ID: 24-11856945_0002_PTD
Published: October 26, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “MOF Biomarker Preservation: Multi-Industry Innovation,” Published Technical Disclosure No. 24-11856945_0002_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856945_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,945.

Background and Problem Solved

The original patent disclosed methods and systems for preparing and preserving biological samples using MOF encapsulants, primarily focused on biomedical research and clinical diagnosis. However, the instability of molecular biomarkers in various biofluids remains a challenge across multiple industries. This invention addresses these limitations by adapting the MOF encapsulant technology to address specific problems in agriculture, food safety, water quality monitoring, vaccine preservation, and air quality monitoring.

Novelty and Inventive Step

The novelty of this invention lies in the adaptation of the MOF encapsulant technology to address specific problems in diverse industries, beyond the original biomedical research and clinical diagnosis applications. The inventive step involves the recognition of the MOF encapsulant's potential in preserving biological samples across multiple industries, and the development of novel systems and methods to achieve this.

Alternative Embodiments and Variations

Alternative embodiments of this invention include the use of different MOF materials, varying the type and ratio of metal ions and organic linkers, and incorporating additional components to enhance the stability and detection capabilities of the biological samples. Variations of the invention may also involve different drying mechanisms, substrates, and sensors to accommodate specific industry requirements.

Potential Commercial Applications and Market

This invention has significant commercial potential across multiple industries, including agriculture, food safety, water quality monitoring, vaccine preservation, and air quality monitoring. The market for MOF-based preservation and detection systems is expected to grow substantially, driven by the increasing demand for efficient and cost-effective solutions in these industries.

CPC Classifications

SectionClassGroup
A A01 A01N1/0231
G G01 G01N1/4044

Original Patent Information

Patent NumberUS 11,856,945
TitleMethods and systems for preparing and preserving a biological sample
Assignee(s)Washington University