MOF Biospecimen Preservation: Advanced Analytical System

Publication ID: 24-11856945_0003_PTD
Published: October 26, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “MOF Biospecimen Preservation: Advanced Analytical System,” Published Technical Disclosure No. 24-11856945_0003_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856945_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,945.

Background and Problem Solved

The original patent disclosed methods and systems for preparing and preserving biological samples using MOF encapsulants. However, the pre-analytical stage remains a significant bottleneck in biomedical research and clinical diagnosis. The present invention addresses this limitation by synergistically combining MOF technology with other distinct technologies to create more powerful systems for preserving, analyzing, and utilizing biological samples.

Novelty and Inventive Step

The novelty of the present invention lies in the synergistic integration of MOF technology with AI, IoT, blockchain, and machine learning technologies, which creates a new, more powerful system for preserving, analyzing, and utilizing biological samples. The inventive step is the recognition that these distinct technologies can be combined to overcome the limitations of the original patent and provide a more comprehensive solution for biomedical research and clinical diagnosis.

Alternative Embodiments and Variations

Alternative embodiments of the invention could include the use of different types of MOF materials, varying the composition of the preserving agent, or incorporating additional technologies such as robotics or virtual reality. Variations could also include adapting the systems for use in different fields, such as agriculture or environmental monitoring.

Potential Commercial Applications and Market

The invention has significant commercial potential in the biomedical research and clinical diagnosis industries, where the availability of high-quality biospecimens is critical. The market for biospecimen preservation and analysis systems is expected to grow substantially in the coming years, driven by advances in personalized medicine, precision diagnostics, and translational research.

CPC Classifications

SectionClassGroup
A A01 A01N1/0231
G G01 G01N1/4044

Original Patent Information

Patent NumberUS 11,856,945
TitleMethods and systems for preparing and preserving a biological sample
Assignee(s)Washington University