Smart MOF Biospecimen Preservation & Monitoring Tech
Legal Citation
Background and Problem Solved
The original patent disclosed methods and systems for preparing and preserving biological samples using MOF encapsulation. However, the existing approach has limitations, including the need for controlled temperature storage and lack of real-time monitoring capabilities. The present invention addresses these limitations by introducing a smart container with integrated MOF encapsulation and real-time biomarker stability monitoring, enabling long-term preservation of biological samples at ambient temperatures.
Novelty and Inventive Step
The present invention's novelty lies in the integration of advanced MOF encapsulation, real-time biomarker stability monitoring, and cloud-based data analytics to enable long-term preservation of high-quality biological samples at ambient temperatures. The inventive step is the combination of these components to create a smart biospecimen preservation and management system, which is not obvious from the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the invention include the use of different MOF materials, varying the design of the smart container, and incorporating additional sensors for monitoring other sample parameters. Variations of the portable biospecimen collection kit may include different substrates, such as paper or fabric, and alternative drying apparatuses.
Potential Commercial Applications and Market
The present invention has significant commercial potential in the biomedical research and clinical diagnostics industries, enabling the preservation and management of high-quality biological samples for extended periods. The target market includes research institutions, hospitals, and pharmaceutical companies, with potential applications in personalized medicine, biomarker discovery, and disease diagnosis.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01N1/0231 |
| G | G01 | G01N1/4044 |
Original Patent Information
| Patent Number | US 11,856,945 |
|---|---|
| Title | Methods and systems for preparing and preserving a biological sample |
| Assignee(s) | Washington University |