MOF Biomarker Preservation: Advanced Molecular Stability Tech

Publication ID: 24-11856945_0008_PTD
Published: October 26, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “MOF Biomarker Preservation: Advanced Molecular Stability Tech,” Published Technical Disclosure No. 24-11856945_0008_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856945_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,945.

Background and Problem Solved

The original patent addressed the poor stability of molecular biomarkers in biological samples during the pre-analytical stage. However, it did not provide solutions for real-time monitoring, decentralized collection and analysis, or personalized medicine applications. This new invention solves these problems by combining MOF encapsulants with cutting-edge technologies.

Novelty and Inventive Step

The new claims introduce the innovative combination of MOF encapsulants with distinct technologies, providing a synergistic effect that enhances the preservation, monitoring, and analysis of biological samples. This integration is non-obvious and goes beyond the original patent's scope.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different MOF types, varying sensor configurations, or alternative AI algorithms. Variations may also involve the integration of additional technologies, such as robotics or augmented reality, to further enhance the systems and methods.

Potential Commercial Applications and Market

This invention has significant commercial potential in the biomedical research, clinical diagnosis, and personalized medicine industries. It can enable the development of new diagnostic tools, improve the quality of biospecimens, and facilitate more effective treatment strategies. The market for these systems and methods is substantial, with potential applications in hospitals, research institutions, and pharmaceutical companies.

CPC Classifications

SectionClassGroup
A A01 A01N1/0231
G G01 G01N1/4044

Original Patent Information

Patent NumberUS 11,856,945
TitleMethods and systems for preparing and preserving a biological sample
Assignee(s)Washington University