Advanced MOF Biospecimen Preservation Technology

Publication ID: 24-11856945_0009_PTD
Published: October 26, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Advanced MOF Biospecimen Preservation Technology,” Published Technical Disclosure No. 24-11856945_0009_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856945_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,945.

Background and Problem Solved

The original patent disclosed methods and systems for preparing and preserving biological samples using metal-organic frameworks (MOFs) encapsulants. However, these methods may not be suitable for specific, narrow market or unique operational environments. This invention addresses the limitations of the original patent by providing tailored solutions for these specialized contexts.

Novelty and Inventive Step

The new claims introduce novel combinations of MOF encapsulant technology with specialized components and operational parameters tailored to specific environments. These adaptations provide a non-obvious improvement over the original patent, enabling the preservation of biological samples in unique contexts.

Alternative Embodiments and Variations

Alternative embodiments of the invention could include using different types of MOFs, varying the molar ratio of precursors, or incorporating additional components to enhance stability or security. Other variations could include adapting the invention for use with different types of biological samples or integrating the technology with existing laboratory equipment.

Potential Commercial Applications and Market

This invention has significant commercial potential in industries such as biomedical research, clinical diagnosis, and biotechnology, particularly in areas requiring specialized sample preservation solutions. Target markets may include government agencies, research institutions, and private companies operating in high-security, extreme weather, disaster relief, high-altitude, or high-radiation environments.

CPC Classifications

SectionClassGroup
A A01 A01N1/0231
G G01 G01N1/4044

Original Patent Information

Patent NumberUS 11,856,945
TitleMethods and systems for preparing and preserving a biological sample
Assignee(s)Washington University