Next-Gen MOF Biopreservation: Decentralized Sample Tech

Publication ID: 24-11856945_0010_PTD
Published: October 26, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Gen MOF Biopreservation: Decentralized Sample Tech,” Published Technical Disclosure No. 24-11856945_0010_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856945_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,945.

Background and Problem Solved

The original patent disclosed methods and systems for preparing and preserving biological samples using metal-organic framework (MOF) encapsulants. However, these methods have limitations in terms of scalability, portability, and adaptability to diverse sample types and collection settings. The new invention addresses these limitations by envisioning next-generation systems that can preserve biological samples in resource-limited settings, decentralized point-of-care settings, and even on the human body.

Novelty and Inventive Step

The new claims introduce several novel and non-obvious features, including the use of wearable, flexible substrates; autonomous, robotic devices; and custom-designed, adaptive MOF materials. These features enable the preservation of biological samples in unprecedented ways, such as on the human body or in decentralized settings.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different types of MOF materials, substrates, or microfluidic devices. Variations may include integrating the systems with artificial intelligence, blockchain technology, or other data management platforms to enhance their functionality and security.

Potential Commercial Applications and Market

The next-generation biological sample preservation systems have vast commercial potential in industries such as healthcare, biotechnology, and pharmaceuticals. They can enable decentralized, point-of-care diagnostics, remote patient monitoring, and personalized medicine, among other applications.

CPC Classifications

SectionClassGroup
A A01 A01N1/0231
G G01 G01N1/4044

Original Patent Information

Patent NumberUS 11,856,945
TitleMethods and systems for preparing and preserving a biological sample
Assignee(s)Washington University