AI-Driven Cryopreservation System: Blockchain & IoT Innovation

Publication ID: 24-11856947_0003_PTD
Published: October 26, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “AI-Driven Cryopreservation System: Blockchain & IoT Innovation,” Published Technical Disclosure No. 24-11856947_0003_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856947_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,947.

Background and Problem Solved

The current manual cryopreservation process is time-consuming, labor-intensive, and prone to human error, resulting in reduced cell viability. The original patent addressed this issue by automating the permeation process, but lacked real-time monitoring, authentication, and optimization capabilities. The new invention solves this problem by integrating AI, IoT, and blockchain technologies to create a more efficient, reliable, and secure cryopreservation system.

Novelty and Inventive Step

The integration of AI, IoT, and blockchain technologies with the original patented device provides a novel and non-obvious solution, enabling real-time monitoring, optimization, and authentication of the cryopreservation process. The use of novel materials and machine learning algorithms further differentiates the invention from the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include using different AI algorithms, IoT sensor configurations, or blockchain platforms. Variations may include integrating additional technologies, such as computer vision or robotics, to further enhance the system's capabilities.

Potential Commercial Applications and Market

The intelligent cryopreservation system has significant commercial potential in the biotechnology, pharmaceutical, and healthcare industries, where cryopreservation is a critical step in cell-based therapies, regenerative medicine, and biobanking. The system's ability to optimize cryopreservation processes, ensure authenticity and integrity, and provide real-time monitoring and control makes it an attractive solution for companies seeking to improve their cryopreservation capabilities.

CPC Classifications

SectionClassGroup
A A01 A01N1/0268
A A01 A01N1/0221
A A01 A01N1/0242
B B01 B01L3/502

Field of Art

Biological material preservation and cryogenic processing, with expertise in cell handling, microfluidic devices, and advanced preservation techniques involving specialized equipment and protocols

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or laboratory technician with advanced training in cell biology, microfluidic device design, and cryopreservation techniques, possessing knowledge of emerging technologies in biotechnology and instrumentation

Obviousness Rationale

A PHOSITA would recognize that integrating digital technologies like AI, IoT, and blockchain with existing cell permeation devices represents a predictable technological evolution. The source patent's fundamental device design provides a clear framework for incorporating advanced monitoring and control systems. The proposed variations leverage standard engineering approaches to enhance the existing technological foundation by adding computational intelligence and tracking capabilities.

Obvious Combinations & Variations

Source Patent Element
Device with reservoirs for biological material permeation
PTD Variation
Adding AI-powered controller to optimize permeation process
Obviousness Reasoning
Implementing computational control for scientific processes is a known technique in biotechnology, representing a predictable application of machine learning to existing instrumentation
Source Patent Element
Clear plastic or translucent device design
PTD Variation
Integrating AI-powered visualization system for real-time monitoring
Obviousness Reasoning
Enhancing visualization through computational analysis is a standard approach in scientific instrumentation, representing an obvious extension of existing device capabilities
Source Patent Element
Biological material permeation device
PTD Variation
Blockchain-based tracking system for ensuring cell authenticity
Obviousness Reasoning
Implementing digital authentication for biological materials is a predictable technological progression in scientific sample management
Source Patent Element
Modular device design with interchangeable components
PTD Variation
Using novel materials like graphene or nanocellulose with integrated IoT sensors
Obviousness Reasoning
Exploring advanced materials and sensor integration represents a standard engineering approach to device improvement
35 U.S.C. § 103 Summary: Based on US Patent 11856947, the proposed technical variations represent obvious modifications to the existing cell permeation device, wherein a person having ordinary skill in the art would readily conceive of integrating computational intelligence, digital tracking, and advanced materials into the foundational device design. The disclosed variations constitute prior art demonstrating the predictable technological progression of biological processing instrumentation through standard engineering methodologies.

Original Patent Information

Patent NumberUS 11,856,947
TitleSystem for automated permeation of a biological material and method of using same
Assignee(s)Cook Medical Technologies LLC