Automated Cryopreservation: Next-Gen Permeation System

Publication ID: 24-11856947_0005_PTD
Published: October 26, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Automated Cryopreservation: Next-Gen Permeation System,” Published Technical Disclosure No. 24-11856947_0005_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856947_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,947.

Background and Problem Solved

The current manual procedure for permeating biological materials with cryoprotectant agents is time-consuming, skill-dependent, and prone to errors. The original patent addressed this issue with a semi-automated device, but its limitations in scalability, customization, and real-time monitoring hinder its widespread adoption. The new invention overcomes these limitations by introducing advanced technologies that enable real-time monitoring, adaptive protocols, and increased automation.

Novelty and Inventive Step

The new claims introduce a paradigm shift in automated permeation technology by integrating AI-driven optimization, real-time monitoring, and modular design. These innovations enable unprecedented levels of automation, customization, and efficiency, making the original patent's semi-automated device obsolete.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different microfluidic materials, alternative machine learning algorithms, or varying swarm robotics configurations. Variations may also include the integration of additional sensors or actuators to further enhance the system's performance and adaptability.

Potential Commercial Applications and Market

The next-generation automated permeation system has vast commercial potential in the fields of cryopreservation, biotechnology, and pharmaceuticals. It can be marketed as a turnkey solution for research institutions, biotech companies, and pharmaceutical manufacturers, enabling them to streamline their cryopreservation processes, reduce costs, and improve product quality.

CPC Classifications

SectionClassGroup
A A01 A01N1/0268
A A01 A01N1/0221
A A01 A01N1/0242
B B01 B01L3/502

Original Patent Information

Patent NumberUS 11,856,947
TitleSystem for automated permeation of a biological material and method of using same
Assignee(s)Cook Medical Technologies LLC