Advanced Olfactory Sensing Tech: Disruptive Biomarker Detection

Publication ID: 24-11856955_0002_PTD
Published: October 26, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Advanced Olfactory Sensing Tech: Disruptive Biomarker Detection,” Published Technical Disclosure No. 24-11856955_0002_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856955_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,955.

Background and Problem Solved

The original patent disclosed binary compositions capable of disrupting Orco-mediated odorant sensing in insects. However, these compositions were limited to agricultural pest control and disease vector management. The current invention expands the scope of this technology to tackle pressing issues in diverse industries, where the detection of volatile organic compounds, cancer biomarkers, environmental pollutants, and disease biomarkers is crucial.

Novelty and Inventive Step

The new claims introduce a paradigm shift by applying the core technology to entirely new fields, demonstrating non-obviousness and inventiveness. The inventive step lies in recognizing the potential of Orco-mediated odorant sensing disruptors beyond insect behavior modification and exploiting their capabilities to address critical challenges in diverse industries.

Alternative Embodiments and Variations

Alternative embodiments may include variations in the composition's formulation, such as nanoparticles, liposomes, or microemulsions, to enhance their efficacy and versatility. Additionally, the invention could be adapted for use in wearable devices, IoT sensors, or lab-on-a-chip platforms to expand its reach and impact.

Potential Commercial Applications and Market

This invention has far-reaching commercial potential in industries such as environmental monitoring, healthcare, food safety, and livestock management. The market for air quality monitoring alone is projected to reach $6.5 billion by 2025, and the invention's ability to address this need, as well as others, positions it for significant market impact and revenue growth.

CPC Classifications

SectionClassGroup
A A01 A01N43/653
A A01 A01N33/06
A A01 A01N2300/00

Original Patent Information

Patent NumberUS 11,856,955
TitleBinary compositions as disruptors of Orco-mediated odorant sensing
Assignee(s)VANDERBILT UNIVERSITY