Advanced Insect Odorant Disruption Nanotechnology
Legal Citation
Background and Problem Solved
The original patent disclosed binary compositions for disrupting odorant sensing in insects, which, although effective, have limitations in terms of bioavailability, stability, and targeted delivery. The present invention addresses these limitations by introducing novel formulations, such as microemulsions, biodegradable nanoparticles, solid dispersions, and controlled-release patches, to improve the efficacy and duration of action of these compositions.
Novelty and Inventive Step
The present invention introduces novel formulations and systems that significantly improve the efficacy, stability, and delivery of binary compositions for disrupting Orco-mediated odorant sensing in insects. The inventive step lies in the combination of these formulations and systems, which provide a synergistic effect that is not obvious from the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the invention may include other formulations, such as liposomes, nanoemulsions, or implantable devices, to further enhance the delivery and efficacy of the binary composition disruptors. Variations of the system may incorporate different monitoring devices or sensors to detect insect activity, or integrate with other pest control methods to provide a comprehensive solution.
Potential Commercial Applications and Market
The present invention has significant commercial potential in the agricultural industry, particularly in pest control and crop protection. The enhanced binary compositions and systems can be used to develop more effective and sustainable solutions for controlling insect populations, reducing crop damage, and mitigating disease transmission. The target market includes agricultural companies, pest control service providers, and government agencies responsible for pest management and public health.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A01 | A01N43/653 |
| A | A01 | A01N33/06 |
| A | A01 | A01N2300/00 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Entomological pest control and chemical composition design, focusing on olfactory disruption technologies for agricultural and disease vector management, requiring expertise in organic chemistry, biochemistry, and insect neurobiology
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degree in chemical engineering or entomology, familiar with insect sensory mechanisms, formulation techniques, and agricultural pest control strategies, possessing practical experience in developing chemical compositions for biological intervention
Obviousness Rationale
The PTD presents predictable variations of the source patent's binary composition technology by applying standard formulation techniques and delivery mechanisms known in the field of pest control. A PHOSITA would recognize that microemulsions, nanoparticle encapsulation, and controlled-release systems are well-established methods for enhancing chemical compound bioavailability and efficacy. The disclosed variations represent routine optimization of the original binary composition concept using standard pharmaceutical and agricultural engineering approaches.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,856,955 |
|---|---|
| Title | Binary compositions as disruptors of Orco-mediated odorant sensing |
| Assignee(s) | VANDERBILT UNIVERSITY |