Advanced Bacillus Pest Control Composition Innovation

Publication ID: 24-11856956_0006_PTD

Published: October 26, 2025

Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Advanced Bacillus Pest Control Composition Innovation,” Published Technical Disclosure No. 24-11856956_0006_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856956_0006_PTD

This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,956.

Background and Problem Solved

The original patent (Compositions comprising recombinant Bacillus cells and an insecticide) has limitations in terms of efficacy, stability, and environmental impact. The present invention addresses these limitations by introducing novel enhancements to the original composition, resulting in improved pest control and reduced environmental burden.

Novelty and Inventive Step

The new claims introduce novel features such as fusion proteins enhancing insecticide efficacy, sustained release formulations, and sensor-triggered dispensers, which are not disclosed in the original patent. These enhancements provide a significant improvement over the prior art, making the invention novel and non-obvious.

Alternative Embodiments and Variations

Alternative embodiments of the invention may include different types of insecticides, varying fusion protein designs, and various plant growth stimulating compounds. Additionally, the composition may be adapted for use in different agricultural settings, such as greenhouses or vertical farming.

Potential Commercial Applications and Market

The enhanced compositions and methods have significant commercial potential in the agricultural industry, particularly in the areas of pest control and crop protection. The invention may be marketed to farmers, agricultural companies, and distributors of pest control products, offering a more efficient, safe, and environmentally friendly solution for pest management.

CPC Classifications

Section	Class	Group
A	A01	A01N63/23
A	A01	A01N37/40
A	A01	A01N37/52
A	A01	A01N41/10
A	A01	A01N43/12
A	A01	A01N43/24
A	A01	A01N43/40
A	A01	A01N43/56
A	A01	A01N43/653
A	A01	A01N43/713
A	A01	A01N47/06
A	A01	A01N47/22
A	A01	A01N47/24
A	A01	A01N47/34
A	A01	A01N57/08
A	A01	A01N57/14
A	A01	A01N63/50
A	A01	A01N51/00
A	A01	A01N55/00

Section 103 Obviousness Analysis (PHOSITA)

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Field of Art

Agricultural biotechnology, specifically microbial pest control and recombinant microorganism engineering for agricultural applications, focusing on Bacillus-based insecticidal compositions

Person of Ordinary Skill (PHOSITA) Profile

A PhD or MS-level microbiologist with expertise in genetic engineering, microbial biotechnology, and agricultural pest management, familiar with recombinant DNA techniques, protein fusion strategies, and insecticide formulation technologies

Obviousness Rationale

A person of ordinary skill would recognize that the PTD's variations represent predictable extensions of the source patent's core technology, involving routine engineering techniques for enhancing microbial insecticide compositions through protein fusion, sustained release strategies, and targeted delivery mechanisms that are well-established in agricultural biotechnology.

Obvious Combinations & Variations

Source Patent Element

Recombinant Bacillus cells expressing fusion proteins with exosporium targeting sequences

PTD Variation

Engineering Bacillus cells to produce fusion proteins that enhance insecticide efficacy by at least 20%

Obviousness Reasoning

Modifying protein fusion strategies to improve insecticide performance represents a predictable optimization using standard protein engineering techniques known in the art

Source Patent Element

Composition comprising Bacillus cells and insecticides like flupyradifurone

PTD Variation

Adding sustained release formulation and sensor-triggered dispensing mechanisms

Obviousness Reasoning

Developing controlled-release agricultural treatments is a known approach for improving pesticide application efficiency, representing an obvious design choice for a skilled practitioner

Source Patent Element

Bacillus-based insecticidal composition with specific protein expressions

PTD Variation

Incorporating plant growth stimulating compounds to enhance overall agricultural performance

Obviousness Reasoning

Combining pest control with plant growth enhancement is a well-established strategy in agricultural biotechnology, representing a logical and predictable combination of known techniques

Source Patent Element

Recombinant Bacillus cells expressing specific protein sequences

PTD Variation

Engineering proteins to improve insecticide solubility by at least 30%

Obviousness Reasoning

Enhancing chemical solubility through protein engineering is a standard technique in biotechnology, representing a routine optimization approach for a skilled researcher

Source Patent Element

Insecticidal composition with specific Bacillus cell characteristics

PTD Variation

Developing sensor-triggered dispensing systems for targeted pest management

Obviousness Reasoning

Integrating sensing technologies with agricultural treatments is a predictable technological advancement within precision agriculture approaches

35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. § 103, the variations disclosed in this publication would have been obvious to a person having ordinary skill in the art at the time of invention, with a reasonable expectation of success, when considering the teachings of US Patent 11856956 in combination with routine biotechnological engineering techniques and known agricultural pest management strategies.

Original Patent Information

Patent Number	US 11,856,956
Title	Compositions comprising recombinant Bacillus cells and an insecticide
Assignee(s)	BASF SE