Recombinant Bacillus: Multi-Industry Biotech Innovation

The original patent focused on compositions comprising recombinant Bacillus cells and an insecticide for agricultural purposes. However, the full potential of these cells has not been explored in other industries. This invention addresses the limitations of the original patent by applying the core technology to new, unrelated fields, thereby expanding its commercial reach and social impact.

The new claims introduce novel applications and use cases that were not considered in the original patent, thereby providing a non-obvious expansion of the technology's scope. The inventive step lies in recognizing the potential of recombinant Bacillus cells in unrelated fields and adapting the core technology to address specific challenges in each industry.

Alternative embodiments may include variations in the type of insecticide used, the specific exosporium targeting sequence, or the fusion protein's design. The invention could also be implemented using different Bacillus species or strains, or by incorporating additional components to enhance its efficacy.

The invention has significant commercial potential in controlled-environment agriculture, human health, bioremediation, pest control, and pharmaceuticals, with potential markets including vertically-stacked plant growth facilities, gut health supplements, bioremediation services, precision agriculture, and pharmaceutical companies.