Published Technical Disclosure Archive

Advanced Bacillus Subtilis Strain for Animal Feed Innovation

Publication ID: 24-11856970_0001_PTD
Published: October 26, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Advanced Bacillus Subtilis Strain for Animal Feed Innovation,” Published Technical Disclosure No. 24-11856970_0001_PTD, Published October 26, 2025, available at https://archive.pr1or.art/24-11856970_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,856,970.

Background and Problem Solved

The original patent disclosed the use of Bacillus subtilis for inhibiting bacterial colonization or infection in animals. However, there is still a need for further improvements to overcome the limitations of the original invention, such as enhancing the strain's growth-inhibiting properties, antimicrobial activity, and shelf life of animal feed. The present invention addresses these limitations by introducing novel adjuvants, synergistic antibiotics, prebiotic components, and real-time monitoring systems to create a more effective and efficient solution.

Novelty and Inventive Step

The new claims introduce novel and non-obvious improvements to the original Bacillus subtilis strain, including the use of adjuvants, synergistic antibiotics, prebiotic components, and real-time monitoring systems. These enhancements provide a significant departure from the original invention, offering better growth-inhibiting properties, antimicrobial activity, and overall animal health benefits.

Alternative Embodiments and Variations

Alternative embodiments of the invention could include different types of adjuvants, antibiotics, or prebiotic components. Additionally, the invention could be implemented using different strains of Bacillus subtilis or other microorganisms. The real-time monitoring system could also be replaced with alternative detection methods or integrated with other health monitoring systems.

Potential Commercial Applications and Market

The present invention has significant commercial potential in the animal feed industry, particularly in the poultry and swine sectors. The enhanced Bacillus subtilis strain could be marketed as a premium product, offering improved animal health and feed quality benefits. The real-time monitoring system could also be sold as a separate product or integrated into existing health monitoring systems, providing an additional revenue stream.

CPC Classifications

SectionClassGroup
A A23 A23K50/40
A A01 A01N63/22
A A23 A23K10/18
C C12 C12N1/205
C C12 C12R2001/125

Field of Art

Animal feed microbiology, probiotics, and microbiome engineering, with expertise in bacterial strain development, agricultural biotechnology, and microbial interactions in animal nutrition

Person of Ordinary Skill (PHOSITA) Profile

A microbiologist or agricultural biotechnologist with advanced degree, experience in probiotic strain selection, understanding of bacterial interactions, and knowledge of animal feed supplement development

Obviousness Rationale

A person having ordinary skill would recognize that the PTD's variations represent predictable extensions of the source patent's core technology, involving standard techniques of microbial strain enhancement, adjuvant combination, and monitoring systems commonly employed in animal feed probiotic development.

Obvious Combinations & Variations

Source Patent Element
Bacillus subtilis strain DSM 32685 with bacterial growth inhibition properties
PTD Variation
Adding novel adjuvants to enhance growth-inhibiting properties against Staphylococcus species
Obviousness Reasoning
Modifying probiotic strains with performance-enhancing adjuvants is a routine optimization technique in microbial feed supplement design, representing a predictable variation with expected results
Source Patent Element
Method of administering Bacillus subtilis spores in animal feed
PTD Variation
Incorporating synergistic antibiotics to create potent antimicrobial combinations
Obviousness Reasoning
Combining probiotics with complementary antimicrobial agents is a known strategy for enhancing microbiological control, representing an obvious approach for improving bacterial interaction mechanisms
Source Patent Element
Bacterial strain for inhibiting multiple bacterial species in animal gut
PTD Variation
Adding prebiotic components to selectively promote beneficial microorganism growth
Obviousness Reasoning
Manipulating gut microbiome composition through strategic prebiotic inclusion is a standard technique in microbiological engineering, representing a predictable method of enhancing probiotic effectiveness
Source Patent Element
Bacillus subtilis strain with bacterial colonization inhibition properties
PTD Variation
Implementing real-time monitoring systems for detecting gut microbiome changes
Obviousness Reasoning
Integrating sensor technologies with probiotic systems is a foreseeable technological progression, utilizing standard diagnostic and monitoring techniques known in biotechnology
Source Patent Element
Method of improving animal performance through bacterial strain administration
PTD Variation
Extending strain application to feed shelf life preservation and spoilage prevention
Obviousness Reasoning
Applying probiotic technologies to adjacent preservation challenges represents an obvious technological extension within predictable problem-solving boundaries of microbial feed technology
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11856970, a person having ordinary skill in the art would find the variations disclosed in this publication to represent obvious modifications and extensions of the original Bacillus subtilis strain technology, thereby rendering subsequent claims involving similar microbial feed supplement strategies anticipated and non-patentable under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,856,970
TitleBacillus subtilis for animal feed
Assignee(s)Chr. Hansen A/S