Cyclone Technology for Bioreactor Gas Stream Separation

Publication ID: 24-11857140_0002_PTD
Published: November 07, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Cyclone Technology for Bioreactor Gas Stream Separation,” Published Technical Disclosure No. 24-11857140_0002_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857140_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,140.

Summary of the Inventive Concept

This inventive concept applies the core technology of cyclones to separate particles from gas streams in bioreactors, enhancing efficiency and reducing contamination risks.

Background and Problem Solved

The original patent described cyclone technology for surface cleaning apparatuses, which have limitations in terms of scalability, complexity, and contamination risks. The new inventive concept addresses the need for efficient and sterile particle separation in bioreactors, which is critical for maintaining a healthy cell culture environment.

Detailed Description of the Inventive Concept

The inventive concept involves adapting the cyclone technology to operate in a sterile environment, specifically designed for bioreactors. The cyclone chamber is modified to accommodate a gas stream inlet, and the vortex finder is optimized for particle separation in a gas stream. The first end wall provides a first end surface of the cyclone chamber, ensuring efficient particle collection. The cyclone is connected to a particle collection chamber, allowing for efficient separation and collection of particles from the gas stream.

Novelty and Inventive Step

The new inventive concept introduces the novel application of cyclone technology to bioreactors, providing a sterile and efficient means of separating particles from gas streams. The inventive step lies in adapting the cyclone design to operate in a sterile environment, addressing a previously unmet need in the bioreactor industry.

Alternative Embodiments and Variations

Alternative embodiments may include modifying the cyclone chamber shape, adjusting the vortex finder design, or integrating additional features such as sensors or automation systems to optimize particle separation. Variations could include applying the cyclone technology to other industries, such as food processing or pharmaceuticals, where sterile particle separation is critical.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the bioreactor industry, where efficient and sterile particle separation is essential for maintaining a healthy cell culture environment. The target market includes bioreactor manufacturers, biotechnology companies, and research institutions, with potential applications in vaccine development, cell therapy, and regenerative medicine.

CPC Classifications

SectionClassGroup
A A47 A47L9/1666
A A47 A47L9/165

Field of Art

Particle separation technologies, specifically cyclone separation systems for air and gas streams in cleaning and industrial applications, requiring mechanical engineering expertise with knowledge of fluid dynamics and separation techniques

Person of Ordinary Skill (PHOSITA) Profile

A mechanical engineer with expertise in fluid separation technologies, familiar with cyclone design principles, industrial filtration systems, and cross-industry adaptation of separation technologies

Obviousness Rationale

A PHOSITA would recognize that the core cyclone separation principles from the surface cleaning apparatus can be readily adapted to bioreactor gas stream separation by applying known fluid dynamics principles. The fundamental cyclone chamber structure, vortex finding mechanism, and particle collection principles remain substantially unchanged across different application contexts. The sterile environment modification represents a predictable design variation within the skill set of an ordinary practitioner in particle separation technologies.

Obvious Combinations & Variations

Source Patent Element
Cyclone chamber with air inlet and vortex finder for particle separation
PTD Variation
Adapting cyclone design to bioreactor gas stream separation with sterile environment considerations
Obviousness Reasoning
Known technique of transferring separation technology between industrial domains, with predictable results of maintaining core separation mechanics
Source Patent Element
First and second end walls defining cyclone chamber geometry
PTD Variation
Modifying end wall configurations to optimize particle collection in sterile gas streams
Obviousness Reasoning
Routine engineering design choice involving geometric optimization within established cyclone separation principles
Source Patent Element
Dirt collection chamber external to cyclone chamber
PTD Variation
Particle collection chamber integrated with bioreactor system for sterile particle management
Obviousness Reasoning
Straightforward extension of known particle collection techniques, applying standard separation technology principles
Source Patent Element
Surface cleaning apparatus cyclone configuration
PTD Variation
Repurposing cyclone technology for precision gas stream separation in controlled environments
Obviousness Reasoning
Predictable application of established separation technology to alternative technical domains with minimal substantive modification
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857140, a person having ordinary skill in the art would find the disclosed bioreactor cyclone separation system obvious, as the fundamental technical principles of cyclone particle separation remain consistent across industrial applications, with the sterile environment adaptation representing a predictable design variation within the ordinary skill set of a mechanical engineer specializing in fluid separation technologies.

Original Patent Information

Patent NumberUS 11,857,140
TitleCyclone such as for use in a surface cleaning apparatus
Assignee(s)Omachron Intellectual Property Inc.