Fluorophore Observation Systems for Niche Environments

Publication ID: 24-11857164_0004_PTD
Published: November 07, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Fluorophore Observation Systems for Niche Environments,” Published Technical Disclosure No. 24-11857164_0004_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857164_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,164.

Summary of the Inventive Concept

This inventive concept adapts the original fluorophore observation method for specialized, high-stakes environments such as high-security facilities, disaster relief situations, extreme weather conditions, high-altitude environments, and underwater operations.

Background and Problem Solved

The original patent relates to a method and device for observing an object containing a bolus of at least one fluorophore, primarily for neurosurgery applications. However, the original invention lacks specific features and adaptations to address the unique challenges and requirements of niche environments. This inventive concept addresses these limitations by introducing specialized variations and niche solutions.

Detailed Description of the Inventive Concept

The inventive concept comprises a range of systems and methods tailored to specific operational environments. For high-security environments, the system includes a security module to encrypt and authenticate images. In disaster relief situations, the method involves providing a portable medical observation device and generating a report of the object's condition. For extreme weather conditions, the device features a weather-resistant housing and a heating or cooling system. In high-altitude environments, the system incorporates a pressure-resistant housing. Finally, for underwater environments, the method involves providing a waterproof medical observation device and generating a 3D visualization of the object's condition.

Novelty and Inventive Step

The inventive concept's novelty lies in its adaptation of the original fluorophore observation method to address the specific challenges and requirements of niche environments. The inventive step resides in the introduction of specialized components, such as security modules, weather-resistant housings, and pressure-resistant housings, which enable the fluorophore observation system to operate effectively in these unique environments.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different types of fluorophores, adapting the system for use with other medical imaging modalities, or integrating the system with other medical devices. Variations could also include using different encryption protocols for high-security environments or incorporating additional sensors for extreme weather conditions.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including healthcare, defense, disaster relief, and environmental monitoring. The specialized variations and niche solutions offered by this inventive concept can provide a competitive advantage in these markets, enabling organizations to operate more effectively in challenging environments.

CPC Classifications

SectionClassGroup
A A61 A61B1/043
A A61 A61B1/00004
G G06 G06T7/0016
G G06 G06T11/001
A A61 A61B2017/00066
G G06 G06T2207/10016
G G06 G06T2207/10064
G G06 G06T2207/30101
G G06 G06T2207/30104
G G06 G06T2210/41

Field of Art

Medical imaging systems, specifically fluorescence-based diagnostic and observation technologies involving image processing, medical devices for biological specimen analysis, and specialized imaging environments

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical imaging specialist with expertise in optical imaging, signal processing, medical device design, and advanced image analysis techniques, holding advanced degrees in bioengineering or medical technology with 3-5 years professional experience

Obviousness Rationale

A person having ordinary skill would recognize that the source patent's fundamental fluorophore observation method provides a flexible framework that can be readily adapted to different environmental contexts by applying standard engineering design principles. The PTD's variations represent predictable extensions of the original imaging technique, utilizing known technological strategies to modify the base system for specific operational requirements. These adaptations involve straightforward modifications such as adding protective housings, integrating security modules, and adjusting image processing parameters, which would be considered routine design choices for a skilled practitioner.

Obvious Combinations & Variations

Source Patent Element
Time series input frame analysis for fluorophore observation
PTD Variation
Adapting frame analysis for high-security environments with image encryption and authentication
Obviousness Reasoning
Adding security protocols to existing image processing systems is a known technique in medical imaging, representing a predictable technological enhancement with well-established implementation strategies
Source Patent Element
Medical observation device for capturing fluorophore-related images
PTD Variation
Introducing weather-resistant housing and temperature regulation systems
Obviousness Reasoning
Environmental adaptation of medical devices is a standard engineering approach, involving known techniques for protecting sensitive electronic components from external conditions
Source Patent Element
Fluorophore observation method using electronic image coding
PTD Variation
Generating 3D visualizations in underwater and disaster relief environments
Obviousness Reasoning
Extending 2D image processing to 3D reconstruction is a well-established technique in medical imaging, representing a predictable technological progression using known signal processing algorithms
Source Patent Element
Component signal processing for fluorescence intensity analysis
PTD Variation
Integrating additional sensors for extreme environment monitoring
Obviousness Reasoning
Augmenting sensor systems with complementary data collection is a routine design choice for expanding diagnostic capabilities in medical imaging technologies
Source Patent Element
Fluorophore observation method for medical diagnostics
PTD Variation
Adapting system for portable and mobile deployment in disaster relief scenarios
Obviousness Reasoning
Miniaturization and portability of medical imaging systems is a known technological trend, representing a predictable engineering optimization with well-understood implementation strategies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857164, the present published technical disclosure demonstrates that the claimed variations in fluorophore observation systems represent obvious extensions of the prior art, employing standard engineering techniques to adapt a fundamental medical imaging method across diverse operational environments. A person having ordinary skill in the art would recognize these modifications as routine design choices involving predictable technological adaptations, thereby rendering potential derivative claims obvious and non-patentable.

Original Patent Information

Patent NumberUS 11,857,164
TitleMethod, image processor and device for observing an object containing a bolus of a fluorophore
Assignee(s)Leica Instruments (Singapore) Pte Ltd.