Enhanced Fluorophore-Based Object Observation System with AI, IoT, and Blockchain Integration

Publication ID: 24-11857164_0008_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Enhanced Fluorophore-Based Object Observation System with AI, IoT, and Blockchain Integration,” Published Technical Disclosure No. 24-11857164_0008_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857164_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,164.

Summary of the Inventive Concept

A novel system and method for observing objects containing a bolus of at least one fluorophore, integrating AI-based machine learning, IoT-enabled communication, blockchain-based data storage, and new material-based illumination to provide enhanced real-time image analysis, secure data sharing, and 3D reconstruction capabilities.

Background and Problem Solved

The original patent disclosed a method and device for observing an object containing a bolus of at least one fluorophore. However, this invention had limitations in terms of image analysis, data storage, and sharing. The new inventive concept addresses these limitations by synergistically combining the original patent's concept with AI, IoT, blockchain, and new materials to create a more powerful and efficient system.

Detailed Description of the Inventive Concept

The new system comprises an image processor integrated with an AI-based machine learning module for real-time image analysis, a multi-spectral or hyperspectral camera for capturing a field of view, and an illumination system for illuminating the field of view with fluorescence excitation wavelengths. The system can also include a blockchain-based data storage system for securely storing and sharing observation data and an IoT-enabled communication module for transmitting observation data to remote locations. The AI-based machine learning module analyzes the input frames and generates a 3D reconstruction of the object, which can be displayed on a blockchain-based augmented reality platform.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and new materials, which is not obvious from the original patent. The inventive step lies in the synergistic combination of these distinct technologies to create a more powerful and efficient system for observing objects containing a bolus of at least one fluorophore.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, various types of cameras, or alternative blockchain platforms. Variations of the system could be implemented for different medical or industrial applications, such as neurosurgery, cancer diagnosis, or material inspection.

Potential Commercial Applications and Market

The enhanced fluorophore-based object observation system has significant commercial potential in the medical and industrial sectors. The system can be used in neurosurgery, cancer diagnosis, and material inspection, providing a competitive advantage in terms of image analysis, data storage, and sharing. The target market includes hospitals, research institutions, and industrial companies.

CPC Classifications

SectionClassGroup
A A61 A61B1/043
A A61 A61B1/00004
G G06 G06T7/0016
G G06 G06T11/001
A A61 A61B2017/00066
G G06 G06T2207/10016
G G06 G06T2207/10064
G G06 G06T2207/30101
G G06 G06T2207/30104
G G06 G06T2210/41

Field of Art

Medical imaging and diagnostic technologies, specifically fluorescence-based object observation systems, involving interdisciplinary skills in medical optics, image processing, machine learning, and advanced sensing technologies

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with advanced degrees in biomedical engineering, medical imaging, or computer science, possessing expertise in image processing algorithms, medical diagnostic technologies, and emerging computational techniques

Obviousness Rationale

A PHOSITA would recognize that integrating AI, IoT, and blockchain technologies into the existing fluorophore observation method represents a predictable extension of known imaging techniques. The source patent's foundational method of fluorophore-based object observation provides a clear technical framework that naturally invites computational and networking enhancements. The proposed variations represent logical technological progressions using standard engineering design choices and readily available computational technologies.

Obvious Combinations & Variations

Source Patent Element
Method for processing electronically coded still images of an object containing a fluorophore
PTD Variation
Adding AI-based machine learning module for real-time image analysis and 3D reconstruction
Obviousness Reasoning
AI image processing is a known technique in medical imaging, and applying machine learning to enhance fluorescence image analysis would be an obvious improvement for a PHOSITA seeking more sophisticated diagnostic capabilities
Source Patent Element
Observation method using input frames and component signal processing
PTD Variation
Implementing multi-spectral and hyperspectral camera technologies for enhanced image capture
Obviousness Reasoning
Expanding imaging technologies to capture broader spectral ranges is a predictable evolution in medical imaging, representing a standard approach to improving diagnostic resolution and information extraction
Source Patent Element
Electronic image processing of fluorophore-containing objects
PTD Variation
Integrating blockchain-based data storage and IoT communication modules
Obviousness Reasoning
Secure data management and remote transmission are standard technological improvements in medical diagnostic systems, representing a logical extension of existing electronic processing capabilities
Source Patent Element
Fluorescence threshold and component signal weighting techniques
PTD Variation
Implementing augmented reality platforms for 3D reconstruction visualization
Obviousness Reasoning
Visualization enhancement through advanced display technologies is a predictable design choice for medical imaging systems seeking to improve diagnostic information presentation
Source Patent Element
Medical observation device for fluorophore-based imaging
PTD Variation
Introducing new material-based illumination systems for fluorescence excitation
Obviousness Reasoning
Material science innovations in illumination technologies represent a standard approach to improving signal quality and diagnostic precision in medical imaging systems
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857164 and the disclosed technological variations, a person of ordinary skill in the art would find the proposed system and method extensions obvious and non-patentable. The incremental technological improvements represent predictable combinations of known techniques in medical imaging, machine learning, and communication technologies, thereby rendering subsequent claims obvious under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,164
TitleMethod, image processor and device for observing an object containing a bolus of a fluorophore
Assignee(s)Leica Instruments (Singapore) Pte Ltd.