Intelligent Biopsy Platform with Adaptive Aspiration and Real-time Tissue Analysis

Publication ID: 24-11857171_0010_PTD
Published: November 07, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Intelligent Biopsy Platform with Adaptive Aspiration and Real-time Tissue Analysis,” Published Technical Disclosure No. 24-11857171_0010_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857171_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,171.

Summary of the Inventive Concept

A next-generation biopsy device that integrates AI-driven navigation, real-time tissue analysis, and adaptive aspiration to optimize sample quality, minimize tissue damage, and enable personalized tissue engineering and regeneration therapies.

Background and Problem Solved

The original biopsy device with aspiration valve, as described in the original patent, has limitations in terms of sample quality and tissue damage. The new inventive concept addresses these limitations by introducing an adaptive aspiration valve that dynamically adjusts suction pressure based on real-time tissue sampling data, ensuring optimal sample quality and minimizing tissue damage.

Detailed Description of the Inventive Concept

The intelligent biopsy platform consists of an adaptive aspiration valve that adjusts suction pressure in real-time based on tissue sampling data, an AI-driven navigation system for precise and efficient sampling, a real-time tissue analysis system with integrated spectrometer and machine learning-based classification algorithm, and a modular design with interchangeable instrument sets and drive units. The platform also features an integrated 3D printing module for in-situ creation of customized tissue scaffolds and implants.

Novelty and Inventive Step

The new claims introduce a paradigm shift in biopsy technology by integrating AI-driven navigation, real-time tissue analysis, and adaptive aspiration, making the original inventive concept obsolete. The inventive step lies in the dynamic adjustment of suction pressure based on real-time tissue sampling data, enabling optimal sample quality and minimizing tissue damage.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in the AI-driven navigation system, such as using different machine learning algorithms or incorporating additional sensors. The real-time tissue analysis system could be modified to include additional analytical techniques, such as Raman spectroscopy or fluorescence microscopy. The modular design could be adapted for use in different medical specialties or applications.

Potential Commercial Applications and Market

The intelligent biopsy platform has significant commercial potential in the medical device industry, particularly in the fields of oncology, neurology, and orthopedics. The platform's ability to optimize sample quality, minimize tissue damage, and enable personalized tissue engineering and regeneration therapies could revolutionize the field of diagnostic medicine and tissue sampling.

CPC Classifications

SectionClassGroup
A A61 A61B10/0275
A A61 A61B10/0283
A A61 A61B2010/0208

Original Patent Information

Patent NumberUS 11,857,171
TitleBiopsy device with aspiration valve
Assignee(s)Hologic, Inc.