Adaptive Aspiration Systems for Enhanced Clot Removal

Publication ID: 24-11857208_0010_PTD

Published: November 07, 2025

Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Adaptive Aspiration Systems for Enhanced Clot Removal,” Published Technical Disclosure No. 24-11857208_0010_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857208_0010_PTD

This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,208.

Summary of the Inventive Concept

The inventive concept introduces a next-generation aspiration technology that leverages artificial intelligence, machine learning, and real-time feedback to optimize clot removal while minimizing damage to surrounding blood vessels.

Background and Problem Solved

The original patent described a device for aspirating fluid from a body lumen, but it had limitations in adapting to varying clot compositions and sizes. The new inventive concept addresses these limitations by incorporating advanced sensors, neural networks, and dynamic aspiration profiles to ensure more effective and safe clot removal.

Detailed Description of the Inventive Concept

The system features a neural network-trained aspiration device that learns from historical aspiration data to adaptively optimize vacuum levels for effective clot removal. The device is equipped with an integrated sensor to detect clot composition and adjust aspiration force accordingly, providing real-time feedback to the user. The catheter system also includes a dynamically adjustable aspiration profile, modified in response to changes in clot morphology detected by an onboard imaging module. Additionally, the device incorporates an artificial intelligence-driven control system that predicts and prevents clogging of the aspiration pathway based on fluid flow patterns and clot properties. The modular aspiration platform integrates multiple aspiration modes, including ultrasound-assisted aspiration and laser-assisted aspiration, to enable personalized treatment strategies for various clot types and sizes.

Novelty and Inventive Step

The new claims introduce a paradigm shift in aspiration technology by integrating AI, machine learning, and real-time feedback to optimize clot removal. The inventive concept's novelty lies in its ability to adapt to varying clot compositions and sizes, ensuring more effective and safe clot removal compared to the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in sensor types, neural network architectures, and aspiration profile algorithms. Additionally, the system could be adapted for use in various medical applications, such as cardiac, neurovascular, or peripheral vascular procedures.

Potential Commercial Applications and Market

The adaptive aspiration system has significant commercial potential in the medical device industry, particularly in the areas of cardiovascular and neurovascular interventions. The system's ability to optimize clot removal while minimizing damage to surrounding blood vessels could lead to improved patient outcomes, reduced procedure times, and increased adoption rates.

CPC Classifications

Section	Class	Group
A	A61	A61B17/22
A	A61	A61M5/3129
A	A61	A61M5/3137
A	A61	A61B2017/22079

Section 103 Obviousness Analysis (PHOSITA)

▼

Field of Art

Medical device engineering, specifically interventional medical devices for fluid aspiration and clot removal in vascular procedures, requiring expertise in catheter design, fluid dynamics, sensor integration, and medical imaging technologies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with advanced degree, specialized knowledge in interventional medical device design, familiar with neural network applications, sensor technologies, and fluid aspiration techniques in vascular interventions

Obviousness Rationale

A PHOSITA would recognize that integrating AI-driven adaptive control and real-time sensing into existing aspiration catheter technologies represents a predictable evolution of medical device design. The source patent establishes fundamental aspiration device architecture, while the PTD applies well-known machine learning and sensor integration techniques to optimize existing mechanical principles. These modifications represent incremental improvements using standard engineering approaches in medical device innovation.

Obvious Combinations & Variations

Source Patent Element

Syringe barrel with fluid passage and plunger mechanism for aspirating fluids

PTD Variation

Adding neural network-trained adaptive vacuum level optimization

Obviousness Reasoning

Applying machine learning to optimize existing mechanical fluid aspiration is a known technique in medical device engineering, representing a predictable application of computational methods to improve device performance

Source Patent Element

Basic catheter aspiration system for removing fluids from body lumens

PTD Variation

Incorporating integrated sensors to detect clot composition and dynamically adjust aspiration force

Obviousness Reasoning

Sensor-based feedback control is a standard design approach in medical devices, with numerous precedents for real-time performance modification based on detected physiological parameters

Source Patent Element

Single lumen catheter for fluid aspiration

PTD Variation

Modular aspiration platform supporting multiple aspiration modes like ultrasound and laser assistance

Obviousness Reasoning

Combining multiple treatment modalities is a common strategy in medical device design, representing a finite set of known techniques for enhancing therapeutic effectiveness

Source Patent Element

Basic fluid aspiration mechanism

PTD Variation

AI-driven control system predicting and preventing aspiration pathway clogging

Obviousness Reasoning

Predictive maintenance and clog prevention using computational methods are standard engineering approaches in fluid handling systems, representing an obvious extension of existing technological capabilities

Source Patent Element

Catheter design for fluid removal

PTD Variation

Onboard imaging module for detecting and responding to clot morphology changes

Obviousness Reasoning

Integrating imaging technologies for real-time diagnostic feedback is a well-established technique in interventional medical devices, representing a predictable technological enhancement

35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857208 and the disclosed technological variations, a person having ordinary skill in the art would find the claimed adaptive aspiration system with neural network optimization, sensor-based feedback, and multi-modal treatment capabilities to be obvious variations of existing medical device technologies, thus rendering potential derivative patent claims anticipated and non-patentable under 35 U.S.C. Section 103.

Original Patent Information

Patent Number	US 11,857,208
Title	Systems and methods for aspirating from a body lumen
Assignee(s)	Silk Road Medical, Inc.