Enhanced Clot Retrieval Device with Real-time Clot Sensing and Adaptive Radial Force Control

Publication ID: 24-11857210_0001_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Clot Retrieval Device with Real-time Clot Sensing and Adaptive Radial Force Control,” Published Technical Disclosure No. 24-11857210_0001_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857210_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,210.

Summary of the Inventive Concept

An improved clot retrieval device that incorporates a clot-sensing mechanism and adaptive radial force control to ensure efficient and safe clot removal from blood vessels, addressing the limitations of existing devices.

Background and Problem Solved

The original patent for a clot retrieval device has limitations in effectively engaging and removing clots from blood vessels. The device's radial force exerted by the clot embedding cells may not be optimal for various clot properties, leading to inefficient or unsafe clot retrieval. This new inventive concept addresses these limitations by introducing a clot-sensing mechanism that detects clot properties and adjusts the radial force accordingly, enabling precise control over the clot retrieval process.

Detailed Description of the Inventive Concept

The enhanced clot retrieval device comprises an expandable structure with a constrained delivery configuration, an expanded clot engaging deployed configuration, and an at least partially constrained clot pinching configuration. The device further includes a clot-sensing mechanism, such as a pressure sensor, that provides real-time feedback to the operator. This feedback enables the operator to adjust the radial force exerted by the clot embedding cells to optimize clot retrieval based on clot properties and vessel anatomy. The device may also include a control unit with a predictive algorithm that anticipates clot behavior and adjusts the radial force proactively, reducing the risk of clot fragmentation or embolization.

Novelty and Inventive Step

The new inventive concept introduces the clot-sensing mechanism and adaptive radial force control, which are not present in the original patent. This combination of features enables real-time feedback and precise control over the clot retrieval process, making the device more efficient and safer to use.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include different types of clot-sensing mechanisms, such as optical or ultrasonic sensors, or varying configurations of the expandable structure and clot embedding cells. Additionally, the control unit's predictive algorithm could be trained on various datasets to improve its accuracy and adaptability.

Potential Commercial Applications and Market

The enhanced clot retrieval device has significant commercial potential in the medical device industry, particularly in the field of neurointerventional and cardiovascular treatments. The device's improved efficiency and safety features could lead to increased adoption and market share, with potential applications in hospitals, clinics, and research institutions.

CPC Classifications

SectionClassGroup
A A61 A61B17/221
A A61 A61B90/39
A A61 A61F2/013
A A61 A61B17/320725
A A61 A61B2017/00867
A A61 A61B2017/2215
A A61 A61B2017/2217
A A61 A61B2017/22034
A A61 A61B2017/22079
A A61 A61B2017/22094
A A61 A61B2090/3966
A A61 A61F2002/016
A A61 A61F2230/008
A A61 A61F2230/0091

Field of Art

Medical device engineering, specifically interventional vascular devices for clot retrieval and endovascular surgical techniques, requiring advanced biomedical engineering, mechanical design, and medical device development skills

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with expertise in medical device design, vascular intervention technologies, advanced materials, sensor integration, and control systems for minimally invasive medical devices, typically holding a Master's or PhD in biomedical/mechanical engineering

Obviousness Rationale

A person having ordinary skill would recognize that integrating real-time sensing and adaptive force control into an existing clot retrieval device represents a predictable technological enhancement. The source patent's detailed structural design provides a clear foundation for incorporating sensor-based feedback mechanisms. The proposed variations represent logical extensions of existing medical device control strategies that would be apparent to a skilled practitioner seeking to improve device performance and safety.

Obvious Combinations & Variations

Source Patent Element
Expandable structure with variable radial force configurations for clot engagement
PTD Variation
Adding a pressure sensor to dynamically adjust radial force based on real-time clot properties
Obviousness Reasoning
Sensor integration for adaptive control is a known technique in medical device design, representing a predictable technological improvement to enhance device performance
Source Patent Element
Clot embedding cells with differential radial force characteristics
PTD Variation
Implementing a control unit with predictive algorithm to proactively manage clot engagement forces
Obviousness Reasoning
Algorithmic control of medical device parameters is a standard approach for optimizing device interaction with biological tissues, representing an obvious design enhancement
Source Patent Element
Configurable device with multiple deployment configurations
PTD Variation
Introducing multiple sensor types (pressure, optical, ultrasonic) for comprehensive clot property detection
Obviousness Reasoning
Utilizing alternative sensor technologies is a routine design choice for expanding device sensing capabilities, following established medical device engineering practices
Source Patent Element
Proximal section configured for clot pinching and engagement
PTD Variation
Adding real-time operator feedback mechanism to adjust device interaction with clot
Obviousness Reasoning
Providing enhanced user control through sensor-based feedback represents a standard approach to improving medical device usability and precision
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857210 and the published technical disclosure, a person having ordinary skill in the art would find the claimed variations of a clot retrieval device with integrated sensing and adaptive force control to be obvious and anticipated by the existing prior art. The proposed technical enhancements represent predictable technological improvements that would be apparent to a skilled practitioner seeking to optimize medical device performance through sensor integration and algorithmic control strategies.

Original Patent Information

Patent NumberUS 11,857,210
TitleClot retrieval device for removing clot from a blood vessel
Assignee(s)Neuravi Limited