Enhanced Clot Retrieval Device and Methods

The inventive concept presents a series of improvements to the original clot retrieval device, enhancing its efficiency, safety, and effectiveness in removing acute blockages from blood vessels.

The original patent, 'Clot retrieval device for removing clot from a blood vessel,' provided a solution for removing acute blockages from blood vessels. However, it had limitations in terms of clot dissolution, retrieval forces, and capture efficiency. The new inventive concept addresses these limitations by introducing an expandable structure coated with a thrombolytic agent, controlled oscillation, and a spiral geometry proximal section, among other enhancements.

The enhanced clot retrieval device features an expandable structure coated with a thrombolytic agent to facilitate clot dissolution during retrieval. The device can be deployed in a blood vessel and then subjected to controlled oscillation to dislodge the clot. Additionally, the device may be integrated with a guidewire featuring a built-in pressure sensor to monitor and optimize clot removal forces. The proximal section of the expandable structure can have a spiral geometry to enhance clot capture and retrieval efficiency. Furthermore, the device can be used in conjunction with localized heat treatment to enhance clot removal.

The new inventive concept introduces several novel features, including the use of thrombolytic agents, controlled oscillation, and spiral geometry, which are not present in the original patent. These enhancements provide a significant improvement in clot retrieval efficiency, safety, and effectiveness, thereby constituting an inventive step.

Alternative embodiments of the inventive concept may include varying the type and amount of thrombolytic agent used, adjusting the frequency and amplitude of the controlled oscillation, or modifying the spiral geometry of the proximal section. Additionally, the device could be designed for use in different vessel sizes or types, or integrated with other clot removal technologies.

The enhanced clot retrieval device and methods have significant commercial potential in the medical device industry, particularly in the areas of neurovascular and cardiovascular interventions. The target market includes hospitals, clinics, and medical research institutions, with potential for widespread adoption and revenue growth.