Published Technical Disclosure Archive

Enhanced Clot Retrieval Device and Methods

Publication ID: 24-11857210_0006_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Clot Retrieval Device and Methods,” Published Technical Disclosure No. 24-11857210_0006_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857210_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,210.

Summary of the Inventive Concept

The inventive concept presents a series of improvements to the original clot retrieval device, enhancing its efficiency, safety, and effectiveness in removing acute blockages from blood vessels.

Background and Problem Solved

The original patent, 'Clot retrieval device for removing clot from a blood vessel,' provided a solution for removing acute blockages from blood vessels. However, it had limitations in terms of clot dissolution, retrieval forces, and capture efficiency. The new inventive concept addresses these limitations by introducing an expandable structure coated with a thrombolytic agent, controlled oscillation, and a spiral geometry proximal section, among other enhancements.

Detailed Description of the Inventive Concept

The enhanced clot retrieval device features an expandable structure coated with a thrombolytic agent to facilitate clot dissolution during retrieval. The device can be deployed in a blood vessel and then subjected to controlled oscillation to dislodge the clot. Additionally, the device may be integrated with a guidewire featuring a built-in pressure sensor to monitor and optimize clot removal forces. The proximal section of the expandable structure can have a spiral geometry to enhance clot capture and retrieval efficiency. Furthermore, the device can be used in conjunction with localized heat treatment to enhance clot removal.

Novelty and Inventive Step

The new inventive concept introduces several novel features, including the use of thrombolytic agents, controlled oscillation, and spiral geometry, which are not present in the original patent. These enhancements provide a significant improvement in clot retrieval efficiency, safety, and effectiveness, thereby constituting an inventive step.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include varying the type and amount of thrombolytic agent used, adjusting the frequency and amplitude of the controlled oscillation, or modifying the spiral geometry of the proximal section. Additionally, the device could be designed for use in different vessel sizes or types, or integrated with other clot removal technologies.

Potential Commercial Applications and Market

The enhanced clot retrieval device and methods have significant commercial potential in the medical device industry, particularly in the areas of neurovascular and cardiovascular interventions. The target market includes hospitals, clinics, and medical research institutions, with potential for widespread adoption and revenue growth.

CPC Classifications

SectionClassGroup
A A61 A61B17/221
A A61 A61B90/39
A A61 A61F2/013
A A61 A61B17/320725
A A61 A61B2017/00867
A A61 A61B2017/2215
A A61 A61B2017/2217
A A61 A61B2017/22034
A A61 A61B2017/22079
A A61 A61B2017/22094
A A61 A61B2090/3966
A A61 A61F2002/016
A A61 A61F2230/008
A A61 A61F2230/0091

Field of Art

Medical device engineering, specifically interventional vascular devices for clot retrieval and treatment, encompassing device design, material science, and minimally invasive medical technologies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with expertise in interventional medical device design, familiar with vascular catheterization techniques, material properties, and advanced medical device manufacturing processes, typically holding a master's or doctoral degree with 3-5 years of specialized experience

Obviousness Rationale

A person having ordinary skill in the art would recognize that the published technical disclosure represents predictable variations and combinations of known techniques in clot retrieval device design. The proposed modifications leverage standard engineering approaches to enhance device functionality, utilizing well-understood principles of medical device optimization such as surface coating, controlled mechanical manipulation, and integrated sensing technologies.

Obvious Combinations & Variations

Source Patent Element
Expandable structure with variable radial force configurations for clot engagement
PTD Variation
Adding thrombolytic agent coating to the expandable structure surface
Obviousness Reasoning
Surface modification of medical devices is a known technique, and applying pharmacologically active coatings to improve device performance is a predictable solution in interventional medical device design
Source Patent Element
Clot retrieval device with configurable geometry for vessel navigation
PTD Variation
Introducing spiral geometry in the proximal section to enhance clot capture
Obviousness Reasoning
Geometric optimization of medical device structures is a routine design choice, and modifying device cross-sectional profiles to improve functional performance represents standard engineering problem-solving
Source Patent Element
Expandable structure capable of multiple configuration states
PTD Variation
Implementing controlled oscillation and localized heat treatment during device deployment
Obviousness Reasoning
Mechanical and thermal interventions are well-known techniques in medical device technologies, and combining mechanical manipulation with thermal effects represents a logical extension of existing clot removal strategies
Source Patent Element
Clot retrieval device designed for vessel navigation and engagement
PTD Variation
Integrating a guidewire with built-in pressure sensing capabilities
Obviousness Reasoning
Sensor integration in medical devices is a standard approach, and adding real-time monitoring capabilities represents an incremental improvement using known technological approaches
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857210 and the published technical disclosure, a person having ordinary skill in the art would find the claimed variations obvious, as they represent predictable combinations of known techniques in medical device design. The proposed modifications constitute routine engineering solutions that would be apparent to a skilled practitioner, thereby rendering potential patent claims obvious and anticipatable by the existing prior art.

Original Patent Information

Patent NumberUS 11,857,210
TitleClot retrieval device for removing clot from a blood vessel
Assignee(s)Neuravi Limited