Enhanced Cryogenic Needle System with Real-Time Tissue Monitoring and Automation

Publication ID: 24-11857239_0006_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Cryogenic Needle System with Real-Time Tissue Monitoring and Automation,” Published Technical Disclosure No. 24-11857239_0006_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857239_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,239.

Summary of the Inventive Concept

The present inventive concept relates to a cryogenic needle system with advanced features for precise and controlled cooling of target tissues, ensuring improved treatment efficacy and safety. The system integrates real-time tissue monitoring, automated freeze zone regulation, and enhanced safety features to overcome the limitations of existing cryogenic treatment systems.

Background and Problem Solved

The original patent, 'Cryogenic needle with freeze zone regulation,' provides a foundation for cryogenic tissue remodeling. However, it has limitations in terms of precision, control, and safety. The present inventive concept addresses these limitations by introducing advanced features that enable real-time tissue monitoring, automated freeze zone regulation, and enhanced safety measures.

Detailed Description of the Inventive Concept

The enhanced cryogenic needle system comprises a temperature sensor to monitor the temperature of the target tissue and adjust the coolant flow accordingly. Additionally, the system includes a built-in thermal imaging system to visualize the target tissue and optimize the cooling zone in real-time. An integrated neural stimulator temporarily immobilizes muscles and nerves in the target tissue zone, enhancing safety and effectiveness. The system also features automated freeze zone regulation using machine learning algorithms to analyze patient data and optimize cooling parameters. Furthermore, a retractable heater element allows for rapid warming of the target tissue to a desired temperature, enabling more precise control over cooling and warming cycles and reducing the risk of tissue damage.

Novelty and Inventive Step

The present inventive concept introduces several novel and non-obvious features that distinguish it from the original patent. These include the integration of real-time tissue monitoring, automated freeze zone regulation, and enhanced safety measures, which collectively provide a more precise, controlled, and safe cryogenic treatment experience.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in sensor types, thermal imaging modalities, and neural stimulation protocols. Additionally, the system could be adapted for use in different tissue types or treatment indications, such as dermatological, orthopedic, or oncological applications.

Potential Commercial Applications and Market

The enhanced cryogenic needle system has significant commercial potential in the medical aesthetics and dermatology markets, where it can be used to treat a range of cosmetic conditions. The system's advanced features and improved safety profile make it an attractive option for clinicians and patients seeking more effective and minimally invasive treatments.

CPC Classifications

SectionClassGroup
A A61 A61B18/02
A A61 A61B2017/00473
A A61 A61B2018/00029
A A61 A61B2018/00041
A A61 A61B2018/00648
A A61 A61B2018/00714
A A61 A61B2018/00738
A A61 A61B2018/00744
A A61 A61B2018/00779
A A61 A61B2018/00791
A A61 A61B2018/00898
A A61 A61B2018/00994
A A61 A61B2018/0262
A A61 A61B2018/0293

Field of Art

Medical device technologies for cryogenic tissue treatment, specifically focused on precision cooling systems for dermatological and therapeutic applications, requiring expertise in thermal engineering, medical device design, and minimally invasive treatment methodologies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with advanced degrees in bioengineering or medical technology, possessing knowledge of thermal control systems, sensor integration, and minimally invasive treatment techniques, with experience in developing precision medical instrumentation

Obviousness Rationale

A person having ordinary skill would recognize that the PTD's variations represent predictable extensions of the source patent's core cryogenic needle technology by applying known sensor integration, machine learning optimization, and thermal control techniques to enhance the existing cryogenic treatment methodology. The disclosed improvements represent incremental advancements that would be apparent to a skilled practitioner seeking to refine tissue cooling technologies.

Obvious Combinations & Variations

Source Patent Element
Needle probe with coolant supply system regulated by a valve for controlling cooling zone
PTD Variation
Adding temperature sensor and real-time coolant flow adjustment mechanism
Obviousness Reasoning
Integrating feedback-controlled valve systems is a standard engineering approach for precision thermal management, representing a predictable optimization of existing coolant regulation techniques
Source Patent Element
Cryogenic tissue treatment method with cooling zone regulation
PTD Variation
Implementing machine learning algorithms to analyze and optimize cooling parameters
Obviousness Reasoning
Applying computational optimization techniques to medical device control is a known strategy for improving treatment precision, representing an obvious application of contemporary data analysis methods
Source Patent Element
Needle probe for tissue cooling
PTD Variation
Incorporating integrated thermal imaging and neural stimulation capabilities
Obviousness Reasoning
Combining complementary medical sensing and intervention technologies is a standard approach for enhancing treatment safety and effectiveness, utilizing well-established interdisciplinary medical engineering principles
Source Patent Element
Cryogenic cooling method with temperature monitoring
PTD Variation
Adding retractable heater element for precise warming cycles
Obviousness Reasoning
Implementing bidirectional thermal control represents a logical extension of existing temperature management strategies, solving known limitations in tissue treatment precision
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857239 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed cryogenic needle system improvements obvious and anticipated, as the PTD demonstrates that the proposed modifications represent predictable technological refinements achievable through standard medical device engineering practices, thereby rendering subsequent claims of novelty invalid under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,239
TitleCryogenic needle with freeze zone regulation
Assignee(s)Pacira CryoTech, Inc.