Intelligent Cryogenic Tissue Remodeling System

Publication ID: 24-11857239_0010_PTD
Published: November 07, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Intelligent Cryogenic Tissue Remodeling System,” Published Technical Disclosure No. 24-11857239_0010_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857239_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,239.

Summary of the Inventive Concept

A next-generation cryogenic system that dynamically adjusts cryogenic temperatures based on real-time tissue response feedback, machine learning algorithms, and personalized treatment recommendations to optimize treatment outcomes for a wide range of cosmetic and medical applications.

Background and Problem Solved

The original cryogenic needle with freeze zone regulation patent (US [insert number]) had limitations in achieving optimal treatment outcomes due to its inability to adapt to individual skin characteristics and tissue response. The new inventive concept addresses this limitation by integrating advanced imaging techniques, machine learning algorithms, and real-time tissue response feedback to provide personalized and optimized treatment outcomes.

Detailed Description of the Inventive Concept

The Intelligent Cryogenic Tissue Remodeling System comprises a needle probe with a freeze zone regulation module that dynamically adjusts cryogenic temperatures based on real-time tissue response feedback. The module utilizes machine learning algorithms to predict optimal cryogenic temperatures for a specific treatment area and integrates with a patient database to provide personalized treatment recommendations based on individual skin characteristics. The system employs advanced imaging techniques to identify and target specific lesion structures for optimal treatment outcomes. The module regulates the coolant supply system to maintain the cooling zone within an allowable size tolerance, ensuring precise and controlled treatment.

Novelty and Inventive Step

The new claims introduce the concept of dynamic temperature adjustment based on real-time tissue response feedback, machine learning algorithms, and personalized treatment recommendations, which is not present in the original patent. This represents a significant paradigm shift in cryogenic tissue remodeling, enabling more accurate and effective treatment outcomes.

Alternative Embodiments and Variations

Alternative embodiments of the Intelligent Cryogenic Tissue Remodeling System could include variations in the type of imaging techniques used, the machine learning algorithms employed, and the integration with different patient databases or electronic health records systems. Additionally, the system could be adapted for use in various medical specialties, such as dermatology, oncology, or orthopedics.

Potential Commercial Applications and Market

The Intelligent Cryogenic Tissue Remodeling System has significant commercial potential in the medical aesthetics and cosmetic industries, as well as in various medical specialties. The system's ability to provide personalized and optimized treatment outcomes could revolutionize the treatment of skin lesions, cosmetic defects, and other medical conditions, offering a competitive advantage in the market.

CPC Classifications

SectionClassGroup
A A61 A61B18/02
A A61 A61B2017/00473
A A61 A61B2018/00029
A A61 A61B2018/00041
A A61 A61B2018/00648
A A61 A61B2018/00714
A A61 A61B2018/00738
A A61 A61B2018/00744
A A61 A61B2018/00779
A A61 A61B2018/00791
A A61 A61B2018/00898
A A61 A61B2018/00994
A A61 A61B2018/0262
A A61 A61B2018/0293

Field of Art

Medical device technologies for cryogenic tissue treatment, specifically focused on dermatological and cosmetic interventions involving precision cooling and tissue remodeling techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with expertise in cryogenic systems, thermal regulation technologies, advanced sensing techniques, and machine learning applications in medical treatment optimization

Obviousness Rationale

A PHOSITA would recognize that the PTD's machine learning and dynamic temperature adjustment techniques represent predictable extensions of the source patent's fundamental cryogenic needle probe technology. The core innovation of freeze zone regulation is maintained, with additional computational and adaptive layers that would be considered routine optimization for a skilled practitioner seeking enhanced treatment precision. The systematic approach to dynamically monitoring and adjusting cryogenic parameters follows directly from the source patent's core teachings about controlled tissue cooling.

Obvious Combinations & Variations

Source Patent Element
Needle probe with coolant supply system regulated by a valve to maintain cooling zone size
PTD Variation
Adding machine learning algorithms to predict and dynamically adjust coolant flow based on real-time tissue response
Obviousness Reasoning
Predictable application of computational techniques to an existing controlled cooling system, representing an obvious design improvement using known machine learning methodologies
Source Patent Element
Method for monitoring temperature and power characteristics of cryogenic treatment
PTD Variation
Integrating advanced imaging techniques to identify specific tissue structures for targeted treatment
Obviousness Reasoning
Known technique of enhancing diagnostic precision through computational imaging, representing a straightforward technological progression in medical device design
Source Patent Element
Cryogenic tissue remodeling method with temperature regulation
PTD Variation
Incorporating patient-specific database integration for personalized treatment recommendations
Obviousness Reasoning
Routine application of data-driven personalization techniques to an existing medical treatment methodology, representing an obvious extension of standard medical informatics practices
Source Patent Element
Needle probe with controllable cooling zone
PTD Variation
Implementing real-time tissue response feedback mechanisms for dynamic temperature adjustment
Obviousness Reasoning
Predictable enhancement of existing temperature control systems using known sensor and feedback technologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857239 and the disclosed technological variations, a person of ordinary skill in the art would find the claimed innovations of the Intelligent Cryogenic Tissue Remodeling System to be obvious variations that do not represent a non-obvious technological advancement. The systematic integration of machine learning, personalized treatment algorithms, and dynamic cooling regulation represents a predictable extension of existing cryogenic tissue treatment methodologies.

Original Patent Information

Patent NumberUS 11,857,239
TitleCryogenic needle with freeze zone regulation
Assignee(s)Pacira CryoTech, Inc.