Advanced Cryosurgical Systems with Integrated Predictive Analytics and Therapeutic Agent Delivery

Publication ID: 24-11857240_0005_PTD
Published: November 07, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Advanced Cryosurgical Systems with Integrated Predictive Analytics and Therapeutic Agent Delivery,” Published Technical Disclosure No. 24-11857240_0005_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857240_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,240.

Summary of the Inventive Concept

The present inventive concept discloses next-generation cryosurgical systems that integrate real-time predictive analytics, microfluidic therapeutic agent delivery, and advanced electrolysis protocols to revolutionize cryosurgery and cold surgery treatments.

Background and Problem Solved

The original patent disclosed cryosurgical instruments combining cryosurgery and electrolysis, but had limitations in optimizing treatment protocols and delivering therapeutic agents. The present inventive concept addresses these limitations by introducing neural network-based predictive analytics, microfluidic systems, and advanced electrolysis protocols to enhance treatment outcomes and expand therapeutic capabilities.

Detailed Description of the Inventive Concept

The advanced cryosurgical system comprises a cryosurgical probe, an electrolysis module, and a neural network-based predictive analytics module. The predictive analytics module optimizes cryosurgical treatment and electrolysis protocols in real-time based on tissue temperature, pH, and electrical conductivity data. The system may also include an integrated microfluidic system for delivering therapeutic agents to the target tissue during cryosurgical treatment. Additionally, the system may incorporate a sensor array and data analytics module for real-time monitoring and adjustment of treatment protocols. The inventive concept also encompasses a method for personalized cryosurgery and electrolysis treatment planning using 3D modeling and simulation, as well as a method for cryosurgery-assisted gene editing using electrolysis to enhance gene editing efficiency.

Novelty and Inventive Step

The integration of neural network-based predictive analytics, microfluidic therapeutic agent delivery, and advanced electrolysis protocols in a single cryosurgical system constitutes a significant departure from the original patent. The use of real-time predictive analytics and microfluidic systems enables personalized and optimized treatment protocols, which is a non-obvious improvement over the prior art.

Alternative Embodiments and Variations

Alternative embodiments may include variations in the predictive analytics module, such as using different machine learning algorithms or incorporating additional data sources. The microfluidic system may be replaced with other therapeutic agent delivery mechanisms, such as nanoparticles or electroporation. The system may also be adapted for use in various medical specialties, such as oncology, dermatology, or orthopedics.

Potential Commercial Applications and Market

The advanced cryosurgical system has significant commercial potential in the medical device industry, particularly in the fields of oncology, dermatology, and orthopedics. The system's ability to optimize treatment protocols and deliver therapeutic agents in real-time may lead to improved treatment outcomes, reduced recovery times, and enhanced patient satisfaction. The market potential is substantial, with projected growth in the cryosurgery and cold surgery markets driven by increasing demand for minimally invasive and personalized treatments.

CPC Classifications

SectionClassGroup
A A61 A61B18/02
A A61 A61B2017/00097
A A61 A61B2018/00101
A A61 A61B2018/0262

Original Patent Information

Patent NumberUS 11,857,240
TitleMethods, systems, and apparatuses for cryosurgery, coldsurgery, and electrolysis
Assignee(s)CRYOELECTRIC SCIENCE LTD.