Synergistic Tissue Ablation Systems

Publication ID: 24-11857244_0003_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Tissue Ablation Systems,” Published Technical Disclosure No. 24-11857244_0003_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857244_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,244.

Summary of the Inventive Concept

The inventive concept integrates pulse shape designs for tissue ablation with AI, IoT, blockchain, and nanomaterial technologies to create a more powerful, personalized, and secure system for minimally invasive tissue ablation.

Background and Problem Solved

The original patent disclosed methods, systems, and apparatuses for tissue ablation using pulse shape designs, but was limited to a standalone electrolysis-based approach. The new inventive concept addresses the limitations of the original patent by incorporating distinct technologies to enhance treatment efficacy, patient outcomes, and data management.

Detailed Description of the Inventive Concept

The synergistic tissue ablation system comprises a pulse generator configured to deliver a pulse of a current or a voltage to a treatment site, with a falling edge that comprises an exponential decay. The system integrates AI-powered machine learning algorithms to analyze patient data and generate customized pulse shape designs. An IoT-enabled ablation device delivers the customized pulse to the treatment site. A blockchain-based data storage unit records treatment data and tracks patient outcomes, ensuring secure and transparent data management. A nanomaterial-based sensor unit provides real-time monitoring of treatment efficacy. The system also includes a cloud-based analytics platform for analyzing treatment data and providing predictive insights for personalized medicine.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and nanomaterial technologies with pulse shape designs for tissue ablation, which is not obvious from the original patent. The inventive concept's synergistic combination of these technologies provides a new and non-obvious solution for tissue ablation.

Alternative Embodiments and Variations

Alternative embodiments may include using different AI algorithms or machine learning models to generate customized pulse shape designs. Variations of the system may incorporate additional technologies, such as augmented reality or robotic-assisted surgery, to further enhance treatment outcomes.

Potential Commercial Applications and Market

The synergistic tissue ablation system has commercial potential in the medical device industry, particularly in the fields of oncology, cardiology, and neurology. The system's ability to provide personalized and secure treatment options may attract significant market share and revenue growth.

CPC Classifications

SectionClassGroup
A A61 A61B18/1206
A A61 A61B18/1402
A A61 A61N1/205
A A61 A61N1/327
A A61 A61B5/14539
A A61 A61B2018/00577
A A61 A61B2018/00613
A A61 A61B2018/00827
A A61 A61B2018/00994
A A61 A61B2018/1266
A A61 A61B2018/1472

Field of Art

Biomedical engineering, specifically electrosurgical tissue ablation technologies with a focus on pulse-based interventional medical devices and data management systems

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with expertise in electrosurgical techniques, signal processing, medical data systems, and interdisciplinary technology integration, holding advanced degrees in bioengineering or medical technology

Obviousness Rationale

A PHOSITA would recognize that integrating contemporary digital technologies like AI, IoT, and blockchain with established electrosurgical pulse techniques represents a predictable evolution of medical device design. The core pulse generation methodology remains consistent with the source patent, while the added technological layers provide enhanced monitoring, personalization, and data management capabilities. These technological integrations represent incremental improvements using standard engineering approaches to medical device innovation.

Obvious Combinations & Variations

Source Patent Element
Pulse delivery method with exponential decay falling edge for tissue ablation
PTD Variation
AI-powered customization of pulse shape design based on patient-specific data
Obviousness Reasoning
Applying machine learning to optimize medical device parameters is a known technique in personalized medicine, representing a predictable application of computational methods to existing medical technologies
Source Patent Element
Electroporation-based tissue treatment method
PTD Variation
IoT-enabled ablation device with real-time monitoring and data transmission
Obviousness Reasoning
Integrating network connectivity and remote monitoring into medical devices is a standard approach for improving treatment tracking and patient outcomes
Source Patent Element
Electrosurgical pulse generation technique
PTD Variation
Blockchain-based secure data storage and patient outcome tracking
Obviousness Reasoning
Implementing distributed ledger technologies for medical data management represents a logical extension of existing data security and privacy preservation techniques
Source Patent Element
Tissue ablation method with controlled electrical pulse characteristics
PTD Variation
Nanomaterial-based sensor integration for real-time treatment efficacy monitoring
Obviousness Reasoning
Utilizing advanced sensing technologies to provide enhanced diagnostic capabilities is a predictable improvement in medical device design
Source Patent Element
Electrosurgical pulse delivery methodology
PTD Variation
Cloud-based analytics platform for treatment data analysis and predictive insights
Obviousness Reasoning
Applying cloud computing and big data analytics to medical treatment data represents a standard approach to enhancing clinical decision-making and treatment personalization
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857244 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed tissue ablation system variations obvious and non-patentable. The incremental technological integrations represent predictable applications of known digital technologies to established electrosurgical methodologies, failing to demonstrate the non-obvious innovation required for patent protection.

Original Patent Information

Patent NumberUS 11,857,244
TitleMethods, systems, and apparatuses for tissue ablation using pulse shape designs
Assignee(s)RM2 TECHNOLOGY LLC, Inter Science GmbH