Synergistic Tissue Ablation Systems using AI, IoT, and Novel Materials

Publication ID: 24-11857244_0008_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Tissue Ablation Systems using AI, IoT, and Novel Materials,” Published Technical Disclosure No. 24-11857244_0008_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857244_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,244.

Summary of the Inventive Concept

The inventive concept integrates AI-driven pulse shape design, IoT-enabled ablation devices, and novel materials with enhanced electro-osmotic diffusion properties to create a more powerful and efficient tissue ablation system, offering improved treatment outcomes and reduced complications.

Background and Problem Solved

The original patent disclosed methods, systems, and apparatuses for tissue ablation using pulse shape designs. However, these approaches have limitations, such as the need for manual optimization of pulse shape designs and the potential for electric discharge of gases during treatment. The new inventive concept addresses these limitations by incorporating AI-driven optimization, IoT-enabled real-time monitoring, and novel materials to create a more synergistic and effective tissue ablation system.

Detailed Description of the Inventive Concept

The inventive concept comprises an AI-driven pulse shape design module that integrates with an IoT-enabled ablation device. The AI module optimizes pulse shape designs for synergistic electroporation and electrolysis effects, reducing the need for manual optimization. The IoT-enabled device enables real-time monitoring and data exchange between the device and a cloud-based server, facilitating personalized treatment planning and adaptive tissue ablation. Additionally, the incorporation of novel materials with enhanced electro-osmotic diffusion properties further enhances the system's efficiency and effectiveness. The system can be used for various tissue ablation applications, including cancer treatment and cosmetic procedures.

Novelty and Inventive Step

The new claims introduce the novel combination of AI-driven pulse shape design, IoT-enabled ablation devices, and novel materials, which provides a synergistic effect that is not obvious from the original patent. The integration of these distinct technologies enables a more powerful and efficient tissue ablation system that was not anticipated by the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include the use of blockchain-secured data storage for enhanced data security, or the incorporation of other novel materials with different properties. Variations of the system may be designed for specific tissue ablation applications, such as cardiac ablation or ophthalmic treatments.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the medical device industry, particularly in the areas of cancer treatment, cosmetic procedures, and minimally invasive surgeries. The system's ability to provide improved treatment outcomes and reduced complications makes it an attractive solution for hospitals, clinics, and medical research institutions.

CPC Classifications

SectionClassGroup
A A61 A61B18/1206
A A61 A61B18/1402
A A61 A61N1/205
A A61 A61N1/327
A A61 A61B5/14539
A A61 A61B2018/00577
A A61 A61B2018/00613
A A61 A61B2018/00827
A A61 A61B2018/00994
A A61 A61B2018/1266
A A61 A61B2018/1472

Field of Art

Biomedical engineering, specifically electrosurgical and tissue ablation technologies involving pulse-based electrical interventions, with expertise in electroporation, device control systems, and advanced signal processing

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with advanced degrees in electrical engineering or biomedical engineering, experienced in electrosurgical techniques, signal design, and medical device development, familiar with emerging technologies in AI and IoT medical applications

Obviousness Rationale

A PHOSITA would recognize that integrating AI-driven pulse optimization, IoT monitoring, and advanced materials into tissue ablation represents a predictable technological evolution of the source patent's fundamental electroporation and pulse shape design principles. The core electrolysis and electroporation mechanisms remain consistent, with the PTD merely introducing contemporary technological augmentations that are well-established in medical device engineering. The systematic application of AI and IoT to optimize existing electrosurgical techniques would be considered an obvious extension of known technological improvement strategies.

Obvious Combinations & Variations

Source Patent Element
Pulse shape design with exponential decay and specific electroporation targeting
PTD Variation
AI-driven pulse shape optimization module for dynamically adjusting pulse characteristics
Obviousness Reasoning
Predictable application of machine learning to optimize existing pulse design parameters, representing a known technique for refining signal characteristics
Source Patent Element
Tissue ablation method with electrical pulse delivery
PTD Variation
IoT-enabled real-time monitoring and adaptive treatment control
Obviousness Reasoning
Standard technological progression in medical devices, integrating network connectivity for enhanced treatment precision and data collection
Source Patent Element
Electrolysis and electroporation at electrode interfaces
PTD Variation
Novel materials with enhanced electro-osmotic diffusion properties
Obviousness Reasoning
Routine materials engineering approach to incrementally improving existing technological processes, representing a finite set of predictable material modifications
Source Patent Element
Reversible and irreversible electroporation techniques
PTD Variation
Blockchain-secured data storage for treatment monitoring and analysis
Obviousness Reasoning
Conventional cybersecurity enhancement for medical data management, representing an obvious technological safeguard for sensitive treatment information
Source Patent Element
Electrical pulse delivery for tissue treatment
PTD Variation
Personalized treatment planning using AI-driven patient-specific data analysis
Obviousness Reasoning
Well-established trend in precision medicine of leveraging computational techniques for individualized medical interventions
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857244 and the comprehensive technological extensions disclosed herein, a person having ordinary skill in the art would find the claimed variations obvious and lacking inventive distinctiveness. The systematic integration of AI, IoT, and advanced materials into established electrosurgical pulse design represents a predictable technological progression that does not meet the non-obviousness requirements of patentability under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,244
TitleMethods, systems, and apparatuses for tissue ablation using pulse shape designs
Assignee(s)RM2 TECHNOLOGY LLC, Inter Science GmbH