Synergistic Tissue Ablation and Assessment System with Integrated AI, IoT, and Advanced Materials

Publication ID: 24-11857253_0003_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Tissue Ablation and Assessment System with Integrated AI, IoT, and Advanced Materials,” Published Technical Disclosure No. 24-11857253_0003_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857253_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,253.

Summary of the Inventive Concept

A novel system integrating artificial intelligence, Internet of Things (IoT), blockchain, and advanced nanomaterials to enhance tissue ablation and assessment, providing real-time lesion progression prediction, secure patient data management, and optimized ablation protocols.

Background and Problem Solved

The original patent disclosed a tissue ablation and assessment system with limitations in real-time monitoring, data security, and optimized ablation protocols. The new inventive concept addresses these limitations by synergistically combining distinct technologies to create a more powerful and efficient system.

Detailed Description of the Inventive Concept

The system consists of an AI module for real-time lesion progression prediction, an IoT-enabled data acquisition device for remote monitoring and analysis of ablation signals, a blockchain-secured data storage and transmission system for secure patient data management, and a novel nanomaterial-based antenna electrode for enhanced electromagnetic radiation transmission and reception. The system integrates these components to provide optimized ablation protocols, real-time tissue parameter monitoring, and secure patient data management.

Novelty and Inventive Step

The new claims introduce the synergistic combination of AI, IoT, blockchain, and advanced nanomaterials, which is non-obvious and novel compared to the original patent. The inventive step lies in the integration of these distinct technologies to create a more powerful and efficient system for tissue ablation and assessment.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different AI algorithms, IoT protocols, or blockchain architectures. Variations may include the integration of additional technologies, such as machine learning-based predictive analytics or IoT-enabled catheter tracking systems.

Potential Commercial Applications and Market

The synergistic tissue ablation and assessment system has potential commercial applications in the medical device industry, particularly in the fields of cardiology, oncology, and neurology. The target market includes hospitals, clinics, and research institutions.

CPC Classifications

SectionClassGroup
A A61 A61B18/1815
A A61 A61B5/0093
A A61 A61B5/05
A A61 A61B5/0507
A A61 A61B5/0538
A A61 A61B18/1492
A A61 A61B2017/00026
A A61 A61B2017/00039
A A61 A61B2017/00084
A A61 A61B2017/00106
A A61 A61B2018/00023
A A61 A61B2018/00029
A A61 A61B2018/00351
A A61 A61B2018/00577
A A61 A61B2018/00636
A A61 A61B2018/00702
A A61 A61B2018/00773
A A61 A61B2018/00785
A A61 A61B2018/00791
A A61 A61B2018/00827
A A61 A61B2018/00875
A A61 A61B2018/1435
A A61 A61B2018/183
A A61 A61B2018/1823
A A61 A61B2018/1838
A A61 A61B2018/1846
A A61 A61B2018/1853
A A61 A61B2018/1861
A A61 A61B2018/1892
A A61 A61B2090/065
A A61 A61B2218/002
A A61 A61B2576/023

Field of Art

Medical device technologies for tissue ablation, electromagnetic signal processing, and diagnostic imaging systems, requiring advanced knowledge of electrical engineering, medical instrumentation, signal processing, and biomedical technologies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with advanced degrees in electrical engineering or biomedical engineering, possessing expertise in RF/microwave signal transmission, tissue interaction technologies, and medical diagnostic instrumentation

Obviousness Rationale

A PHOSITA would recognize that integrating AI, IoT, and advanced materials into the existing tissue ablation system represents a predictable technological evolution using known techniques for enhancing medical diagnostic technologies. The core signal transmission and tissue assessment principles remain fundamentally consistent with the source patent, with the PTD introducing incremental technological improvements using standard engineering design approaches. The combination of existing technologies to achieve enhanced monitoring and diagnostic capabilities would be considered an obvious extension of the original patent's core technological framework.

Obvious Combinations & Variations

Source Patent Element
Antenna configured for direct electrical tissue contact and signal transmission/reception
PTD Variation
Nanomaterial-based antenna electrode with enhanced electromagnetic radiation transmission capabilities
Obviousness Reasoning
Material science improvements to antenna design represent a predictable optimization using known engineering techniques for signal transmission enhancement
Source Patent Element
Assessment signals transmitted at frequencies of at least 1 MHz
PTD Variation
AI-driven signal processing module for optimized ablation signal transmission and reception
Obviousness Reasoning
Applying machine learning algorithms to signal processing represents a standard technological progression in signal analysis and optimization
Source Patent Element
Tissue assessment system with electrical signal transmission
PTD Variation
IoT-enabled data acquisition and remote monitoring system for ablation signals
Obviousness Reasoning
Integrating network connectivity and remote monitoring technologies is a predictable evolution in medical diagnostic instrumentation
Source Patent Element
Tissue ablation and assessment device with signal generation capabilities
PTD Variation
Blockchain-secured data storage and transmission system for patient data management
Obviousness Reasoning
Implementing secure data management techniques represents a standard approach to addressing privacy and data protection requirements in medical technologies
Source Patent Element
Frequency domain signal analysis for tissue characterization
PTD Variation
Machine learning-based predictive analytics for lesion progression forecasting
Obviousness Reasoning
Applying advanced computational techniques to existing signal analysis methodologies represents a predictable technological enhancement
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857253 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed system improvements obvious and lacking inventive step. The incremental technological enhancements involving AI, IoT, blockchain, and nanomaterial technologies represent predictable combinations of known techniques within the medical device signal processing domain, thereby rendering potential patent claims obvious and non-patentable under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,253
TitleTissue ablation and assessment system and method of use thereof
Assignee(s)The Johns Hopkins University