Advanced Intraocular Physiological Sensing System

Publication ID: 24-11857262_0005_PTD
Published: November 07, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Advanced Intraocular Physiological Sensing System,” Published Technical Disclosure No. 24-11857262_0005_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857262_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,262.

Summary of the Inventive Concept

A next-generation intraocular physiological sensing system capable of continuous, real-time monitoring of multiple physiological parameters, enabling personalized glaucoma management and early disease detection.

Background and Problem Solved

The original patent's intraocular pressure sensing system has limitations in terms of continuous monitoring and real-time analysis. The new inventive concept addresses these limitations by introducing a more advanced system that can continuously measure intraocular pressure, temperature, and oxygen levels, and wirelessly transmit the data for real-time analysis and alert generation.

Detailed Description of the Inventive Concept

The advanced intraocular physiological sensing system consists of an implantable sensor capable of continuously measuring multiple physiological parameters, including intraocular pressure, temperature, and oxygen levels. The sensor wirelessly transmits the data to an external device for real-time analysis using machine learning algorithms. The system can identify patterns indicative of glaucoma progression, generate personalized treatment recommendations, and detect early signs of glaucoma. The system also includes a personalized treatment planning module for generating customized treatment recommendations.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift in intraocular physiological sensing by enabling continuous, real-time monitoring of multiple physiological parameters, and leveraging machine learning algorithms for personalized glaucoma management and early disease detection. The inventive concept is novel and non-obvious compared to the original patent, which only measures intraocular pressure and lacks real-time analysis and machine learning capabilities.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the type and number of physiological parameters measured, using different machine learning algorithms, or integrating the system with other medical devices. Variations could also include using different materials or designs for the implantable sensor, or incorporating additional features such as power harvesting or data storage.

Potential Commercial Applications and Market

The advanced intraocular physiological sensing system has significant commercial potential in the ophthalmology and healthcare industries, particularly in the areas of glaucoma management and early disease detection. The system could be marketed as a premium product for patients requiring continuous monitoring, and could also be used in clinical trials for new glaucoma treatments.

CPC Classifications

SectionClassGroup
A A61 A61B3/16
A A61 A61B3/0025
A A61 A61B5/076
A A61 A61B2560/0257

Field of Art

Medical device engineering, specifically implantable physiological sensors for ophthalmological monitoring, requiring expertise in biomedical engineering, sensor design, wireless data transmission, and machine learning algorithms for medical diagnostics

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with advanced degrees, experience in medical sensor design, knowledge of wireless medical device communication protocols, and understanding of machine learning techniques for medical data analysis

Obviousness Rationale

A person having ordinary skill in the art would recognize that extending the source patent's intraocular pressure sensing system to include multiple physiological parameters and machine learning analysis represents a predictable technological advancement using known techniques in medical sensor design and data processing. The integration of additional sensing capabilities and advanced analytics would be an obvious progression for improving medical monitoring technologies. The proposed variations represent incremental improvements that would be apparent to a skilled practitioner seeking to enhance diagnostic capabilities.

Obvious Combinations & Variations

Source Patent Element
Intraocular pressure sensing implant with wireless data transmission
PTD Variation
Adding multiple physiological parameter measurements (temperature, oxygen levels) to the sensor
Obviousness Reasoning
Expanding sensor capabilities to measure multiple parameters is a known design approach in medical sensing, representing a predictable combination of existing sensing technologies
Source Patent Element
External device for processing sensor data
PTD Variation
Implementing machine learning algorithms for data analysis and predictive diagnostics
Obviousness Reasoning
Applying machine learning to medical sensor data is a well-established technique for identifying patterns and generating diagnostic insights, representing an obvious technological extension
Source Patent Element
Intraocular pressure measurement system
PTD Variation
Creating a personalized treatment planning module based on continuous monitoring
Obviousness Reasoning
Developing personalized medical interventions using sensor data is a standard approach in precision medicine, representing a logical and predictable technological progression
Source Patent Element
Wireless data transmission from implantable sensor
PTD Variation
Real-time data analysis and alert generation for early disease detection
Obviousness Reasoning
Implementing real-time monitoring and alert systems is a standard approach in medical device design, representing an obvious enhancement to existing sensor technologies
Source Patent Element
Basic intraocular pressure sensing system
PTD Variation
Continuous monitoring with advanced data processing capabilities
Obviousness Reasoning
Enhancing sensor systems with continuous monitoring and sophisticated data analysis represents a predictable technological improvement within the field of medical sensing
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857262 and the published technical disclosure, a person having ordinary skill in the art would find the proposed variations in intraocular physiological sensing systems to be obvious and lacking inventive step. The incremental advancements in sensor design, data collection, and analytical capabilities represent predictable technological progressions that would be readily apparent to a skilled practitioner in medical device engineering and would therefore fail to meet the non-obviousness requirements under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,262
TitleIntraocular physiological sensor
Assignee(s)Glaukos Corporation