Enhanced Intraocular Physiological Sensors for Glaucoma Management

Publication ID: 24-11857262_0006_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Intraocular Physiological Sensors for Glaucoma Management,” Published Technical Disclosure No. 24-11857262_0006_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857262_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,262.

Summary of the Inventive Concept

The inventive concept discloses a suite of improvements to intraocular physiological sensors, enabling continuous monitoring, personalized treatment, and enhanced safety features for glaucoma patients.

Background and Problem Solved

The original patent, 'Intraocular physiological sensor', provided a foundational approach to measuring intraocular pressure. However, it had limitations in terms of continuous monitoring, personalized treatment, and sensor maintenance. The new inventive concept addresses these limitations by introducing advanced features, such as multi-point pressure measurement, self-cleaning mechanisms, and real-time data transmission.

Detailed Description of the Inventive Concept

The inventive concept comprises multiple components: (1) an implantable intraocular sensor with a self-cleaning mechanism, ensuring accurate measurements over time; (2) a data processing unit that calculates pressure gradients across the eye; (3) a system for personalized glaucoma management, utilizing machine learning algorithms to analyze pressure data and provide tailored treatment recommendations; and (4) a real-time intraocular pressure monitoring system, alerting patients and healthcare providers of abnormal readings. These advancements enable more effective glaucoma diagnosis, monitoring, and treatment.

Novelty and Inventive Step

The new inventive concept introduces several novel features, including the self-cleaning mechanism, pressure gradient calculation, and personalized treatment recommendations. These innovations provide a significant improvement over the original patent, offering enhanced safety, accuracy, and personalized care for glaucoma patients.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in sensor design, data processing algorithms, and notification systems. For example, the sensor could be miniaturized for easier implantation, or the data processing unit could utilize artificial intelligence to identify patterns indicative of glaucoma. Additionally, the notification system could be integrated with existing healthcare infrastructure to facilitate seamless communication between patients and healthcare providers.

Potential Commercial Applications and Market

The enhanced intraocular physiological sensors have significant commercial potential in the ophthalmology and healthcare industries. They could be marketed as a premium product for glaucoma patients, offering improved monitoring and treatment outcomes. The sensors could also be integrated into existing healthcare systems, providing a new revenue stream for healthcare providers and manufacturers.

CPC Classifications

SectionClassGroup
A A61 A61B3/16
A A61 A61B3/0025
A A61 A61B5/076
A A61 A61B2560/0257

Field of Art

Medical device engineering, specifically implantable physiological sensors for ophthalmological monitoring, involving biomedical engineering, microelectronics, and sensor design with expertise in intraocular pressure measurement technologies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with advanced degree, specialized knowledge in medical sensor design, familiarity with microfluidic systems, signal processing algorithms, and implantable medical device miniaturization techniques

Obviousness Rationale

A person having ordinary skill would recognize that the PTD's disclosed variations represent predictable incremental improvements to the source patent's intraocular pressure sensing system. The proposed enhancements like self-cleaning mechanisms, pressure gradient calculations, and machine learning analysis are logical extensions of existing sensor technologies. These modifications would be considered routine optimization strategies within the field of implantable medical sensors.

Obvious Combinations & Variations

Source Patent Element
Intraocular pressure sensing implant for capturing absolute measurements
PTD Variation
Adding a self-cleaning microfluidic channel mechanism to prevent sensor degradation
Obviousness Reasoning
Sensor maintenance is a known challenge in implantable devices, and implementing self-cleaning techniques would be an obvious solution to a PHOSITA seeking to improve measurement reliability
Source Patent Element
External device with data processing capabilities
PTD Variation
Incorporating machine learning algorithms to analyze pressure data and generate personalized treatment recommendations
Obviousness Reasoning
Applying advanced data analysis techniques to medical sensor data represents a predictable application of known machine learning technologies to improve diagnostic capabilities
Source Patent Element
Intraocular pressure measurement system
PTD Variation
Implementing multi-point pressure gradient calculation across different eye regions
Obviousness Reasoning
Expanding measurement techniques to provide more comprehensive diagnostic information is a logical and foreseeable enhancement for medical sensing technologies
Source Patent Element
External data processing and transmission capabilities
PTD Variation
Real-time monitoring system with patient and healthcare provider notification mechanisms
Obviousness Reasoning
Integrating alert systems with medical sensors is a well-established approach for improving patient care and represents an obvious technological progression
Source Patent Element
Intraocular pressure sensing implant
PTD Variation
Miniaturization and enhanced wireless transmission capabilities
Obviousness Reasoning
Continuous miniaturization and improved wireless communication are standard evolutionary paths in implantable medical device design, representing predictable technological improvements
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857262 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed innovations obvious and non-patentable. The proposed enhancements represent routine optimization and predictable combinations of known techniques in intraocular sensing technologies, thereby rendering subsequent claims obvious under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,262
TitleIntraocular physiological sensor
Assignee(s)Glaukos Corporation