Personalized Atrial Fibrillation Ablation 2.0: AI-Driven, Real-Time Adaptive Therapy

Publication ID: 24-11857263_0005_PTD
Published: November 07, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Atrial Fibrillation Ablation 2.0: AI-Driven, Real-Time Adaptive Therapy,” Published Technical Disclosure No. 24-11857263_0005_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857263_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,263.

Summary of the Inventive Concept

This next-generation atrial fibrillation ablation technology leverages machine learning, real-time 3D imaging, and adaptive catheter design to provide a more effective, personalized, and minimally invasive treatment for patients.

Background and Problem Solved

The original patent's personalized atrial fibrillation ablation device, while innovative, has limitations in terms of its reliance on pre-procedure planning and fixed ablation patterns. This new inventive concept addresses these limitations by integrating AI-driven predictive analytics, real-time imaging, and adaptive catheter technology to create a more dynamic, responsive, and effective treatment approach.

Detailed Description of the Inventive Concept

The system comprises a machine learning module that analyzes a patient's 3D heart model to predict optimal ablation patterns, a catheter device configured to create the predicted ablation patterns in real-time, and a sensor array that monitors the effectiveness of the ablation treatment. The adaptive ablation panel adjusts its shape and size in real-time to conform to a patient's unique pulmonary vein anatomy, ensuring a more precise and effective treatment. The system also includes a real-time 3D imaging module that provides continuous guidance during the ablation procedure, enabling the navigation module to optimize catheter placement and reduce procedural time.

Novelty and Inventive Step

The new claims introduce the novel combination of machine learning, real-time imaging, and adaptive catheter technology, which enables a more dynamic, responsive, and effective treatment approach. This represents a significant departure from the original patent's fixed ablation patterns and pre-procedure planning, providing a more personalized and minimally invasive treatment for patients.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different machine learning algorithms, alternative imaging modalities, or variations in the adaptive catheter design. Additionally, the system could be integrated with other diagnostic tools, such as ECG or echocardiography, to further enhance its predictive capabilities.

Potential Commercial Applications and Market

This next-generation atrial fibrillation ablation technology has significant commercial potential in the electrophysiology and cardiology markets, with potential applications in hospitals, clinics, and research institutions. The market for atrial fibrillation ablation devices is expected to grow significantly in the coming years, driven by the increasing prevalence of atrial fibrillation and the need for more effective, minimally invasive treatment options.

CPC Classifications

SectionClassGroup
A A61 A61B34/10
A A61 A61B18/1492
A A61 A61B2017/00526
A A61 A61B2018/00375
A A61 A61B2018/00577
A A61 A61B2034/104
A A61 A61B2034/105
A A61 A61B2090/374
A A61 A61B2090/378
A A61 A61B2090/3762
A A61 A61M25/0009

Field of Art

Medical device technology for cardiac intervention, specifically focused on atrial fibrillation treatment using interventional catheter systems with advanced imaging and ablation techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or interventional cardiologist with expertise in electrophysiology, medical imaging, catheter design, and machine learning applications in medical device technology

Obviousness Rationale

A PHOSITA would recognize that integrating machine learning, real-time adaptive imaging, and dynamic catheter design represents a predictable technological progression from the original personalized ablation patent, leveraging known techniques in medical device innovation to enhance treatment precision and patient outcomes.

Obvious Combinations & Variations

Source Patent Element
Three-dimensional model of patient's heart used for personalized ablation planning
PTD Variation
Machine learning module that dynamically analyzes 3D heart model to predict and adjust ablation patterns in real-time
Obviousness Reasoning
Applying machine learning to existing 3D modeling techniques is a known approach for improving medical diagnostic and interventional technologies, representing an obvious enhancement to existing personalized treatment methods
Source Patent Element
Fixed ablation panel configured for atrial fibrillation treatment
PTD Variation
Adaptive ablation panel that adjusts shape and size in real-time to conform to patient's pulmonary vein anatomy
Obviousness Reasoning
Developing responsive medical devices that can dynamically adapt to individual patient anatomy is a predictable design evolution in interventional medical technology
Source Patent Element
Ablation device with ostial fitment elements for pulmonary vein engagement
PTD Variation
Real-time 3D imaging module providing continuous guidance for catheter navigation and placement
Obviousness Reasoning
Integrating advanced imaging technologies to improve device placement and procedural accuracy represents an obvious technological improvement in medical device design
Source Patent Element
Patient-specific ablation approach for treating atrial fibrillation
PTD Variation
Machine learning-based risk assessment for predicting atrial fibrillation recurrence using patient's 3D heart model and ablation data
Obviousness Reasoning
Extending personalized medical technologies to include predictive risk analysis is a natural and obvious progression in precision medicine approaches
Source Patent Element
Electrode configuration for monitoring ablation treatment
PTD Variation
Sensor array that provides real-time monitoring and feedback on ablation treatment effectiveness
Obviousness Reasoning
Implementing continuous monitoring technologies is a predictable enhancement in medical device design, particularly for complex interventional procedures
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857263 and the technological context of personalized atrial fibrillation treatment, the variations disclosed herein would be considered obvious to a person having ordinary skill in the art, as they represent predictable technological advancements utilizing known techniques in medical device design, machine learning, and interventional imaging technologies.

Original Patent Information

Patent NumberUS 11,857,263
TitlePersonalized atrial fibrillation ablation