Neuromodulation-inspired solutions for agriculture, microbiology, and environmental remediation

Publication ID: 24-11857275_0002_PTD
Published: November 07, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Neuromodulation-inspired solutions for agriculture, microbiology, and environmental remediation,” Published Technical Disclosure No. 24-11857275_0002_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857275_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,275.

Summary of the Inventive Concept

The inventive concept applies the core technology of targeted neuromodulation to novel industries, including agriculture, microbiology, and environmental remediation, to enhance crop growth, microorganism productivity, and bioremediation efficiency.

Background and Problem Solved

The original patent disclosed systems and methods for targeted neuromodulation in brain stimulation therapies. However, the limitations of this technology lie in its restricted application to human brain stimulation. The inventive concept addresses this limitation by exploring new applications of the core technology in unrelated fields, where similar principles of targeted stimulation can be applied to achieve desirable outcomes.

Detailed Description of the Inventive Concept

The inventive concept comprises systems and methods for personalized agricultural crop stimulation, targeted neuromodulation of microorganisms, neuromodulation-based pest control, personalized environmental remediation, and targeted neuromodulation of biofilm formation. These novel applications leverage the original patent's technology to identify optimal stimulation targets and provide electromagnetic stimulation to enhance crop growth, microorganism productivity, and bioremediation efficiency, while disrupting pest behavior and biofilm formation.

Novelty and Inventive Step

The inventive concept's novelty lies in its application of targeted neuromodulation principles to novel industries, resulting in a non-obvious expansion of the original patent's technology. The inventive step is the recognition of the potential for targeted stimulation to achieve desirable outcomes in these unrelated fields.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include variations in the type of electromagnetic stimulation, the specific industries or applications targeted, and the integration of additional data sources or sensors to enhance the accuracy of stimulation targets. For example, the use of machine learning algorithms to analyze crop data and predict optimal stimulation targets could further enhance the efficiency of the agricultural crop stimulation system.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the agriculture, microbiology, and environmental remediation industries, where the ability to enhance crop growth, microorganism productivity, and bioremediation efficiency can lead to increased yields, reduced costs, and improved environmental outcomes. The target market includes companies involved in precision agriculture, biotechnology, and environmental consulting.

CPC Classifications

SectionClassGroup
A A61 A61B34/20
A A61 A61B5/0036
A A61 A61B5/055
A A61 A61N1/20
A A61 A61N1/36096
A A61 A61N2/006
G G01 G01R33/4806
G G01 G01R33/5608

Field of Art

Biomedical engineering, neurostimulation technologies, and computational systems for targeted electromagnetic interventions, with expertise in neuroimaging, signal processing, and personalized medical/biological targeting strategies

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degree in bioengineering, neuroscience, or electrical engineering, possessing knowledge of neuroimaging techniques, electromagnetic stimulation protocols, computational data analysis, and interdisciplinary technology translation

Obviousness Rationale

A PHOSITA would recognize the fundamental similarity between targeted neuromodulation principles in the source patent and the PTD's novel application domains. The core technological framework of identifying precise stimulation targets through data analysis and applying electromagnetic interventions remains consistent across biological systems. The extension of neuromodulation techniques to agriculture, microbiology, and environmental contexts represents a predictable technological progression utilizing well-established signal processing and targeting methodologies.

Obvious Combinations & Variations

Source Patent Element
Processor-based system for obtaining patient brain data and identifying stimulation targets
PTD Variation
Applying identical computational targeting methodology to crop, microorganism, and environmental biological systems
Obviousness Reasoning
Predictable application of known computational targeting technique to alternative biological domains, representing a standard technological translation approach
Source Patent Element
Electromagnetic stimulation for treating mental health conditions
PTD Variation
Extending electromagnetic stimulation to enhance crop growth, microorganism productivity, and disrupt pest behaviors
Obviousness Reasoning
Known technique of using targeted electromagnetic interventions, with predictable results across different biological systems following established signal processing principles
Source Patent Element
Discarding irrelevant neuroimaging data to refine stimulation targeting
PTD Variation
Applying similar data filtering techniques to agricultural, microbiological, and environmental biological datasets
Obviousness Reasoning
Standard data analysis approach representing an obvious extension of computational signal processing techniques across different biological domains
Source Patent Element
Personalized stimulation based on individual structural imaging data
PTD Variation
Creating personalized stimulation protocols for crops, microorganisms, and environmental remediation targets
Obviousness Reasoning
Predictable technological progression applying established personalization methodologies to alternative biological contexts
Source Patent Element
Processor-based system for identifying and targeting specific brain parcels
PTD Variation
Identifying and targeting specific biological subsystems in agriculture, microbiology, and environmental contexts
Obviousness Reasoning
Obvious technological translation representing a standard computational approach to targeting biological interventions
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857275 and the disclosed technological framework, a person having ordinary skill in the art would find the proposed variations in agricultural, microbiological, and environmental neuromodulation applications to be obvious extensions of known targeted electromagnetic stimulation techniques, thereby rendering potential claims in these domains anticipated and non-patentable under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,275
TitleSystems and methods for targeted neuromodulation
Assignee(s)The Board of Trustees of the Leland Stanford Junior University