Personalized Brain Stimulation Systems for Next-Generation Neuromodulation
Legal Citation
Summary of the Inventive Concept
A revolutionary neuromodulation system that leverages advanced neuroimaging, machine learning, and real-time brain activity feedback to provide highly effective, personalized brain stimulation therapies for a wide range of neurological and psychiatric disorders.
Background and Problem Solved
The original patent, 'Systems and methods for targeted neuromodulation', introduced a significant advancement in neuromodulation therapy by generating personalized stimulation targets. However, it has limitations in terms of real-time adaptability, precision, and effectiveness. The new inventive concept addresses these limitations by integrating cutting-edge technologies to create a more sophisticated, adaptive, and patient-centric neuromodulation system.
Detailed Description of the Inventive Concept
The new inventive concept consists of a neural network module that generates a personalized brain stimulation therapy plan based on a patient's brain connectivity profile. A stimulation delivery module adapts the therapy plan in real-time to optimize treatment outcomes. The system can be integrated with wearable brain-computer interface devices, cloud-based platforms, and non-invasive optogenetic stimulation devices to provide a comprehensive, adaptive, and highly effective neuromodulation solution.
Novelty and Inventive Step
The new claims introduce a paradigm shift in neuromodulation therapy by incorporating machine learning, real-time brain activity feedback, and advanced neuroimaging. These innovations enable a level of personalization, adaptability, and effectiveness that surpasses the original patent, making the new inventive concept a significant advancement in the field.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different machine learning algorithms, integration with various wearable devices, or the development of novel optogenetic stimulation methods. These variations would ensure broad conceptual coverage and provide a foundation for further innovation and development.
Potential Commercial Applications and Market
The new inventive concept has significant commercial potential in the treatment of neurological and psychiatric disorders, such as depression, anxiety, and Parkinson's disease. The market for neuromodulation therapies is expected to grow substantially in the coming years, and this innovative concept is poised to capture a significant share of that market.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61B34/20 |
| A | A61 | A61B5/0036 |
| A | A61 | A61B5/055 |
| A | A61 | A61N1/20 |
| A | A61 | A61N1/36096 |
| A | A61 | A61N2/006 |
| G | G01 | G01R33/4806 |
| G | G01 | G01R33/5608 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Neurological medical technologies focusing on brain stimulation, neuroimaging, and personalized medical treatment systems, encompassing neurology, medical imaging, signal processing, and machine learning technologies
Person of Ordinary Skill (PHOSITA) Profile
A skilled practitioner with advanced degrees in neuroscience, biomedical engineering, or medical technology, possessing expertise in neuroimaging techniques, brain mapping, machine learning algorithms, and medical device design
Obviousness Rationale
A PHOSITA would recognize that the PTD's variations represent predictable extensions of the source patent's core neuromodulation framework by introducing standard machine learning and real-time feedback techniques commonly applied in brain stimulation technologies. The proposed innovations leverage well-established computational methods to enhance personalization and adaptive treatment strategies. These modifications represent incremental improvements that would be obvious to a skilled practitioner familiar with emerging neurological treatment technologies.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,275 |
|---|---|
| Title | Systems and methods for targeted neuromodulation |
| Assignee(s) | The Board of Trustees of the Leland Stanford Junior University |