Personalized Neuromodulation Systems with AI, IoT, Blockchain, and Novel Materials

Publication ID: 24-11857275_0008_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Neuromodulation Systems with AI, IoT, Blockchain, and Novel Materials,” Published Technical Disclosure No. 24-11857275_0008_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857275_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,275.

Summary of the Inventive Concept

This inventive concept integrates cutting-edge technologies to create a novel, personalized neuromodulation system, enhancing treatment outcomes for patients with various mental health conditions.

Background and Problem Solved

The original patent disclosed a targeted neuromodulation system, but it lacked the power of synergistic combinations with other technologies. This new inventive concept addresses the limitations of the original patent by incorporating AI, IoT, blockchain, and novel materials to create a more effective and secure system.

Detailed Description of the Inventive Concept

The system comprises a wearable brain-computer interface (BCI) device, a cloud-based AI engine, and a blockchain-based secure data storage system. The AI engine analyzes brain activity data from the BCI device and generates a personalized stimulation target, which is securely stored and shared with authorized healthcare providers via the blockchain-based system. Additionally, the system may include an IoT-enabled TMS device and a real-time brain activity monitoring system, enabling real-time optimization of therapy outcomes. Furthermore, the use of novel materials, such as graphene-based electrodes, enhances signal quality and accuracy of stimulation target generation.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and novel materials with the original targeted neuromodulation system, providing a synergistic combination that enhances the system's effectiveness, security, and personalization capabilities.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different AI algorithms, varying blockchain architectures, or incorporating other novel materials. Variations may also include adapting the system for different mental health conditions or integrating with other medical devices.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential in the neuromodulation therapy market, particularly in the treatment of mental health conditions such as major depressive disorder. The integration of AI, IoT, blockchain, and novel materials provides a competitive advantage in terms of effectiveness, security, and personalization, making it an attractive solution for healthcare providers and patients.

CPC Classifications

SectionClassGroup
A A61 A61B34/20
A A61 A61B5/0036
A A61 A61B5/055
A A61 A61N1/20
A A61 A61N1/36096
A A61 A61N2/006
G G01 G01R33/4806
G G01 G01R33/5608

Original Patent Information

Patent NumberUS 11,857,275
TitleSystems and methods for targeted neuromodulation
Assignee(s)The Board of Trustees of the Leland Stanford Junior University