Adaptive Neuromodulation Systems for Specialized Environments

Publication ID: 24-11857275_0009_PTD
Published: November 07, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Adaptive Neuromodulation Systems for Specialized Environments,” Published Technical Disclosure No. 24-11857275_0009_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857275_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,275.

Summary of the Inventive Concept

A system and method for targeted neuromodulation therapy adapted for specific, narrow markets or unique operational environments, ensuring effective treatment in diverse settings.

Background and Problem Solved

While existing neuromodulation systems have shown promise, they often fall short in addressing the needs of patients in high-security, disaster relief, extreme weather, remote, or high-stress environments. The present inventive concept builds upon the original patent's personalized stimulation targets, but incorporates novel adaptations to cater to these specialized contexts.

Detailed Description of the Inventive Concept

The adaptive neuromodulation system comprises a processor and memory containing a targeting application. The application directs the processor to obtain patient brain data, adapt stimulation targets based on real-time environmental data, and provide brain stimulation therapy tailored to the specific environment. In the disaster relief setting, the system features a portable neuromodulation device. For high-security needs, patient brain data is encrypted and transmitted to a secure server. In extreme weather conditions, the system incorporates a weather-resistant device and adjusts stimulation parameters accordingly. For remote or underserved areas, a satellite connection enables data transmission and reception of personalized stimulation targets. In high-stress environments, a wearable device detects stress levels and adjusts stimulation targets.

Novelty and Inventive Step

The new claims introduce novel adaptations to the original patent's personalized stimulation targets, including portable devices, real-time environmental data integration, encryption, satellite connectivity, and stress level detection. These innovations provide a non-obvious solution for effective neuromodulation therapy in specialized environments.

Alternative Embodiments and Variations

Alternative embodiments may include adapting the system for use in other niche environments, such as space exploration or search and rescue operations. Variations could involve integrating additional sensors or data sources to further refine stimulation targets.

Potential Commercial Applications and Market

The adaptive neuromodulation system has significant commercial potential in various industries, including disaster relief, high-security, healthcare, and aerospace. The system's ability to provide effective treatment in diverse settings opens up new market opportunities and revenue streams.

CPC Classifications

SectionClassGroup
A A61 A61B34/20
A A61 A61B5/0036
A A61 A61B5/055
A A61 A61N1/20
A A61 A61N1/36096
A A61 A61N2/006
G G01 G01R33/4806
G G01 G01R33/5608

Field of Art

Neuromodulation and brain stimulation technologies, encompassing medical imaging, neurological treatment systems, and personalized therapeutic interventions with expertise in neuroimaging, signal processing, and medical device design

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or neurotechnology specialist with advanced degrees in bioengineering, neuroscience, or medical electronics, possessing knowledge of brain mapping, stimulation techniques, and adaptive medical device design

Obviousness Rationale

A PHOSITA would recognize that the PTD's environmental adaptations represent predictable extensions of the source patent's personalized stimulation targeting framework. The disclosed variations leverage standard engineering techniques of sensor integration, data encryption, and contextual parameter adjustment to enhance neuromodulation delivery. These modifications represent logical refinements to the core technological concept of targeted brain stimulation across diverse operational contexts.

Obvious Combinations & Variations

Source Patent Element
Obtaining patient brain data via structural MRI scans for targeted stimulation
PTD Variation
Integrating real-time environmental data to dynamically adjust stimulation parameters
Obviousness Reasoning
Adaptive parameter modification is a known technique in medical device design, representing a predictable optimization of the original targeting methodology
Source Patent Element
Brain stimulation therapy for treating mental conditions
PTD Variation
Implementing specialized device configurations for disaster relief, high-security, and extreme environments
Obviousness Reasoning
Contextual device adaptation is an obvious design choice for extending medical technology into specialized use cases with finite, identifiable environmental constraints
Source Patent Element
Processor-driven targeting application for personalized stimulation
PTD Variation
Incorporating stress level detection and satellite connectivity for remote data transmission
Obviousness Reasoning
Integrating physiological monitoring and remote communication represents a standard technological enhancement using known telecommunications and biosensing techniques
Source Patent Element
Transcranial magnetic stimulation and electrical stimulation methods
PTD Variation
Developing portable and weather-resistant neuromodulation devices
Obviousness Reasoning
Environmental hardening and miniaturization are predictable engineering improvements for medical devices seeking broader deployment scenarios
Source Patent Element
Patient brain data processing for stimulation targeting
PTD Variation
Implementing data encryption and secure server transmission protocols
Obviousness Reasoning
Security enhancement through data protection is an obvious technological progression for medical information systems
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857275, a person of ordinary skill in the art would find the variations disclosed herein to be obvious extensions of the prior art, rendering potential claims directed to environment-adapted neuromodulation systems anticipated and/or obvious under 35 U.S.C. ยง 103, with a reasonable expectation of success in implementing such adaptive targeting methodologies.

Original Patent Information

Patent NumberUS 11,857,275
TitleSystems and methods for targeted neuromodulation
Assignee(s)The Board of Trustees of the Leland Stanford Junior University