Synergistic Clot Manipulation and Removal System

Publication ID: 24-11857277_0008_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Clot Manipulation and Removal System,” Published Technical Disclosure No. 24-11857277_0008_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857277_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,277.

Summary of the Inventive Concept

A novel, AI-driven, IoT-enabled, blockchain-secured, and nanomaterial-enhanced system for robotically controlled clot manipulation and removal, integrating multiple distinct technologies to create a more powerful and effective treatment solution.

Background and Problem Solved

The original patent addressed the need for robotically controlled clot manipulation and removal, but was limited by its reliance on manual operation and lack of integration with advanced technologies. The new inventive concept solves this problem by combining the original patented system with AI, IoT, blockchain, and nanomaterials to create a more efficient, secure, and personalized treatment approach.

Detailed Description of the Inventive Concept

The synergistic clot manipulation and removal system comprises a robotic arm with a clot-manipulation instrument, integrated with an AI-driven clot analysis module for predicting clot behavior, an IoT-enabled sensor module for monitoring patient vital signs, a blockchain-based secure data storage module for storing patient-specific clot data, and a nanomaterial-based clot-dissolving agent delivery module. The system utilizes machine learning-based patient risk assessment to predict patient-specific clot formation risks and provide personalized treatment recommendations. The real-time imaging module monitors clot dissolution, while the cloud-based data analytics module tracks procedure outcomes.

Novelty and Inventive Step

The new claims introduce the novel combination of AI, IoT, blockchain, and nanomaterials with the original patented system, providing an inventive step beyond the original patent. The integration of these distinct technologies enables a more powerful, efficient, and personalized treatment approach, which is not obvious from the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT sensor configurations, blockchain protocols, or nanomaterials. Variations could also include the integration of additional technologies, such as augmented reality or 5G networks, to further enhance the system's capabilities.

Potential Commercial Applications and Market

The synergistic clot manipulation and removal system has significant commercial potential in the medical device industry, particularly in the areas of cardiovascular and neurovascular treatment. The system's ability to provide personalized, efficient, and secure treatment solutions could disrupt the current market and create new opportunities for growth and innovation.

CPC Classifications

SectionClassGroup
A A61 A61B34/30
A A61 A61B17/12136
A A61 A61B17/3207
A A61 A61B2017/22038
A A61 A61B2034/301
A A61 A61B2034/303
A A61 A61B2090/08021

Field of Art

Medical device technologies for minimally invasive vascular interventions, specifically robotic systems for clot manipulation and removal, requiring expertise in medical robotics, interventional radiology, and advanced medical instrumentation

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or interventional radiologist with advanced degrees, experience in robotic medical device design, knowledge of AI/IoT technologies, and understanding of medical data management systems

Obviousness Rationale

A PHOSITA would recognize that integrating AI, IoT, and data management technologies with existing robotic medical intervention systems represents a predictable technological evolution. The source patent's foundational robotic clot manipulation system provides a clear technical framework for incorporating advanced computational and monitoring technologies. The proposed variations represent incremental improvements using known techniques from adjacent technological domains.

Obvious Combinations & Variations

Source Patent Element
Robotic instrument system with elongate members for clot manipulation
PTD Variation
Adding AI-driven clot analysis module to provide real-time procedural guidance
Obviousness Reasoning
Integrating computational intelligence into medical robotic systems is a known technique for enhancing precision and diagnostic capabilities, representing a predictable technological improvement
Source Patent Element
Instrument system for physical clot modification
PTD Variation
Incorporating nanomaterial-based clot-dissolving agent delivery module
Obviousness Reasoning
Expanding clot treatment capabilities through advanced material technologies is an obvious extension of existing medical intervention strategies, utilizing well-established pharmaceutical and materials science principles
Source Patent Element
Robotic clot manipulation system
PTD Variation
Adding blockchain-secured patient data storage and IoT-enabled monitoring
Obviousness Reasoning
Implementing secure data management and real-time monitoring represents a standard technological progression in medical device design, addressing known requirements for patient safety and procedural documentation
Source Patent Element
Instrument system for clot removal
PTD Variation
Machine learning-based patient risk assessment for personalized treatment recommendations
Obviousness Reasoning
Applying predictive analytics to medical intervention strategies is a recognized approach for improving treatment precision, utilizing well-established machine learning techniques
Source Patent Element
Robotic medical intervention system
PTD Variation
Cloud-based data analytics module for tracking procedure outcomes
Obviousness Reasoning
Implementing centralized data collection and analysis is a standard technological approach for medical device performance evaluation, representing an obvious enhancement to existing systems
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857277 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed system modifications obvious and predictable. The incremental technological enhancements represent standard design choices within the medical robotics domain, utilizing known techniques from computational, materials, and data management technologies to extend the foundational clot manipulation system.

Original Patent Information

Patent NumberUS 11,857,277
TitleRobotically controlled clot manipulation and removal
Assignee(s)Auris Health, Inc.