Adaptive Phase Unwrapping for Cardiac Strain Analysis in Specialized Environments

Publication ID: 24-11857288_0004_PTD
Published: November 07, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Adaptive Phase Unwrapping for Cardiac Strain Analysis in Specialized Environments,” Published Technical Disclosure No. 24-11857288_0004_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857288_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,288.

Summary of the Inventive Concept

A novel approach to phase unwrapping for cardiac strain analysis, tailored to meet the unique demands of high-stress, emergency response, extreme weather, high-security, and disaster relief scenarios.

Background and Problem Solved

The original patent disclosed a method for phase unwrapping in dense MRI using deep learning, which, while effective, has limitations in its applicability to specialized environments. The inventive concept addresses these limitations by adapting the phase unwrapping method to operate in real-time, utilizing portable MRI scanners, and incorporating dedicated hardware and software components to ensure robustness and security in these niche scenarios.

Detailed Description of the Inventive Concept

The inventive concept comprises a deep learning module configured to process displacement encoded MRI data in real-time, utilizing a dedicated GPU for accelerated processing. The system is designed to operate in high-stress environments, emergency response situations, extreme weather conditions, high-security environments, and disaster relief scenarios. The deep learning-based phase unwrapping algorithm is optimized for each specific scenario, ensuring accurate and reliable cardiac strain analysis. In high-security environments, the system encrypts displacement encoded MRI data, while in disaster relief scenarios, the system utilizes a portable MRI scanner and a dedicated CNN for epicardial and endocardial segmentation.

Novelty and Inventive Step

The inventive concept's novelty lies in its adaptation of the original phase unwrapping method to specialized environments, incorporating unique components and configurations to address the specific challenges of each scenario. The inventive step resides in the tailored design of the system and algorithm to ensure robustness, security, and accuracy in these niche applications.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of other deep learning architectures, such as recurrent neural networks (RNNs) or transformers, to improve the accuracy and efficiency of the phase unwrapping algorithm. Variations could also include the integration of additional sensors or data sources to enhance the system's robustness and adaptability in different environments.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including healthcare, emergency response, and disaster relief. The system's ability to operate in high-stress environments and provide accurate cardiac strain analysis in real-time makes it an attractive solution for hospitals, emergency responders, and disaster relief organizations.

Field of Art

Medical imaging, specifically cardiac magnetic resonance imaging (MRI) with advanced signal processing and deep learning techniques for strain analysis

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with expertise in medical imaging, signal processing, deep learning neural networks, and MRI data analysis, typically holding a PhD or advanced engineering degree with specialized knowledge in medical image processing

Obviousness Rationale

A person having ordinary skill in the art would recognize that the published technical disclosure represents predictable variations of the source patent's core deep learning phase unwrapping methodology by adapting the fundamental technique to specialized environmental contexts. The core algorithmic approach remains substantially unchanged, with modifications representing routine engineering adaptations to different operational scenarios. The PTD's variations demonstrate standard design choices that would be apparent to a skilled practitioner familiar with medical imaging and deep learning techniques.

Obvious Combinations & Variations

Source Patent Element
U-Net structured CNN for phase unwrapping in cardiac MRI
PTD Variation
Applying U-Net CNN to specialized environments like emergency response and disaster relief scenarios
Obviousness Reasoning
Transferring a known neural network architecture to different operational contexts represents a predictable design variation with expected performance characteristics
Source Patent Element
Displacement encoded MRI data processing
PTD Variation
Adding real-time processing with dedicated GPU acceleration
Obviousness Reasoning
GPU acceleration for deep learning models is a standard optimization technique known to those skilled in the art, representing an incremental technical improvement
Source Patent Element
Epicardial and endocardial segmentation using CNN
PTD Variation
Implementing segmentation CNN in high-security and extreme environment contexts with data encryption
Obviousness Reasoning
Extending segmentation techniques to different operational environments is a straightforward application of existing image processing methodologies
Source Patent Element
Cardiac strain analysis using MRI displacement encoding
PTD Variation
Using portable MRI scanners in disaster relief and emergency response scenarios
Obviousness Reasoning
Adapting medical imaging equipment to field conditions represents a predictable engineering solution with well-understood design constraints
Source Patent Element
Deep learning phase unwrapping algorithm
PTD Variation
Exploring alternative neural network architectures like RNNs and transformers
Obviousness Reasoning
Investigating alternative neural network designs for signal processing is a standard research approach with predictable exploratory outcomes
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857288 and the published technical disclosure, a person having ordinary skill in the art would find the claimed variations obvious, as the disclosed techniques represent predictable extensions of existing medical imaging and deep learning methodologies, demonstrating no inventive step beyond the routine application of known signal processing techniques to specialized environmental contexts.

Original Patent Information

Patent NumberUS 11,857,288
TitleSystems and methods for phase unwrapping for dense MRI using deep learning
Assignee(s)University of Virginia Patent Foundation