Cardiac Strain Analysis Systems and Methods for Specialized Environments

Publication ID: 24-11857288_0009_PTD
Published: November 07, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Cardiac Strain Analysis Systems and Methods for Specialized Environments,” Published Technical Disclosure No. 24-11857288_0009_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857288_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,288.

Summary of the Inventive Concept

This inventive concept adapts cardiac strain analysis using deep learning for specific, narrow markets or unique operational environments, such as extreme weather conditions, emergency response situations, high-security needs, disaster relief, and remote or isolated areas.

Background and Problem Solved

The original patent disclosed systems and methods for phase unwrapping for dense MRI using deep learning, enabling accurate cardiac strain analysis. However, these methods are limited to general clinical settings and do not account for specialized environments that require adapted solutions. The new inventive concept addresses this limitation by providing tailored systems and methods for cardiac strain analysis in various niche situations.

Detailed Description of the Inventive Concept

The inventive concept comprises systems and methods that integrate MRI scanners and deep learning modules to generate phase images for cardiac strain analysis in specialized environments. For example, in extreme weather conditions, the MRI scanner is configured to acquire displacement encoded MRI data in high winds or extreme temperatures, while the deep learning module generates phase images for strain analysis. In emergency response situations, the method rapidly acquires displacement encoded MRI data and uses a U-Net structured CNN to compute a wrapping label map for strain analysis in real-time. Similarly, in high-security environments, the deep learning module is encrypted to prevent unauthorized access. In disaster relief situations, a portable MRI scanner acquires displacement encoded MRI data, and a CNN configured for epicardial and endocardial segmentation assigns one of three classes to each pixel. In remote or isolated areas, a satellite-enabled MRI scanner acquires displacement encoded MRI data, and the deep learning module is connected to a cloud-based server for remote analysis.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious in its adaptation of cardiac strain analysis using deep learning for specialized environments, which are not addressed by the original patent. The inventive step lies in the tailored design of systems and methods to accommodate unique operational requirements, ensuring accurate and reliable cardiac strain analysis in these niche situations.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different deep learning architectures, such as convolutional neural networks (CNNs) or recurrent neural networks (RNNs), to improve the accuracy and speed of cardiac strain analysis. Variations could also include the integration of additional sensors or data sources, such as electrocardiogram (ECG) or blood pressure data, to enhance the robustness of the analysis.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including healthcare, emergency response, disaster relief, and remote or isolated area services. The adapted systems and methods can provide accurate and reliable cardiac strain analysis in specialized environments, enabling healthcare professionals to make informed decisions in critical situations. The market for these adapted solutions is substantial, given the growing need for specialized healthcare services and the increasing adoption of deep learning in medical imaging.

Field of Art

Medical imaging, specifically cardiac magnetic resonance imaging (MRI) with deep learning techniques for strain analysis, requiring advanced knowledge of signal processing, machine learning, and medical image interpretation

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical imaging specialist with expertise in MRI technologies, deep learning neural networks, signal processing, and cardiac imaging techniques, holding advanced degrees in biomedical engineering, computer science, or related fields

Obviousness Rationale

A PHOSITA would recognize that the PTD's variations represent predictable extensions of the source patent's core deep learning approach to cardiac strain analysis, merely adapting the existing technical framework to different operational contexts by applying known engineering design principles and machine learning techniques to specialized environments.

Obvious Combinations & Variations

Source Patent Element
U-Net structured CNN for computing wrapping label maps in cardiac MRI
PTD Variation
Applying U-Net CNN to real-time emergency response and portable MRI scanning scenarios
Obviousness Reasoning
Adapting existing neural network architectures to different operational contexts is a standard design choice with predictable results in machine learning applications
Source Patent Element
Displacement encoded MRI data acquisition for cardiac strain analysis
PTD Variation
Configuring MRI scanners for extreme weather, high-security, and remote environments
Obviousness Reasoning
Modifying hardware configurations to operate in diverse environments is a routine engineering adaptation using known environmental engineering techniques
Source Patent Element
CNN for epicardial and endocardial segmentation with three-class pixel classification
PTD Variation
Integrating segmentation CNN with portable and satellite-enabled MRI systems
Obviousness Reasoning
Transferring existing segmentation algorithms across different hardware platforms is a predictable application of machine learning techniques
Source Patent Element
Deep learning modules for generating phase images from MRI data
PTD Variation
Adding encryption, cloud connectivity, and remote analysis capabilities
Obviousness Reasoning
Implementing standard cybersecurity and cloud computing techniques to existing medical imaging systems represents an obvious technological evolution
Source Patent Element
Cardiac strain analysis using displacement encoded MRI
PTD Variation
Expanding analysis to include additional sensor integration like ECG and blood pressure data
Obviousness Reasoning
Augmenting medical imaging analysis with complementary physiological data sources is a standard approach in biomedical engineering
35 U.S.C. § 103 Summary: Based on US Patent 11857288's comprehensive disclosure of deep learning techniques for cardiac strain MRI, the present publication demonstrates that the claimed variations represent obvious extensions readily apparent to a person having ordinary skill in medical imaging and machine learning, thus rendering subsequent claims covering similar technical adaptations anticipated and non-patentable under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,288
TitleSystems and methods for phase unwrapping for dense MRI using deep learning
Assignee(s)University of Virginia Patent Foundation