Enhanced Systems and Methods for Optimizing Functional Images of a Lesion Region using Guided Diffuse Optical Tomography
Legal Citation
Summary of the Inventive Concept
An improved system and method for generating optimized functional images of a lesion region using guided diffuse optical tomography, enhancing image quality, speed, and accuracy through adaptive intensity adjustment, machine learning, sparse coding, wavelet transform, and deep learning algorithms.
Background and Problem Solved
The original patent, 'Systems and methods of optimizing functional images of a lesion region using guided diffuse optical tomography', addresses the limitations of breast cancer imaging using diffuse optical tomography (DOT). However, the original patent has inherent limitations, such as fixed optical signal intensity, limited image processing capabilities, and lack of adaptability. The new inventive concept addresses these limitations by introducing adaptive intensity adjustment, advanced image processing algorithms, and improved computational efficiency.
Detailed Description of the Inventive Concept
The enhanced system comprises a DOT device configured to acquire lesion functional data from the lesion region and reference functional data from a healthy tissue region. The DOT device is adapted to adjust the intensity of the optical signal based on the distance between the lesion region and the healthy tissue region. The system also includes a processing unit configured to process the lesion functional data and the reference functional data using machine learning, sparse coding, wavelet transform, or deep learning algorithms to generate optimized functional images. The new claims provide improved image quality, speed, and accuracy, enabling better diagnosis and treatment of breast cancer.
Novelty and Inventive Step
The new inventive concept's novelty lies in the adaptive intensity adjustment, advanced image processing algorithms, and improved computational efficiency, which are not present in the original patent. The inventive step is the combination of these features, which provides a significant improvement over the existing technology.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept include using different machine learning algorithms, sparse coding techniques, wavelet transform methods, or deep learning architectures. Variations of the system could include using different DOT devices, processing units, or image reconstruction algorithms to generate optimized functional images.
Potential Commercial Applications and Market
The enhanced system and method have significant commercial potential in the medical imaging industry, particularly in breast cancer diagnosis and treatment. The target market includes hospitals, clinics, and research institutions, with potential for expansion into other medical imaging applications.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Medical imaging, specifically diffuse optical tomography (DOT) for breast cancer diagnostics, requiring expertise in optical signal processing, image reconstruction algorithms, and medical imaging techniques
Person of Ordinary Skill (PHOSITA) Profile
A skilled practitioner with advanced degrees in biomedical engineering, medical physics, or related fields, possessing knowledge of medical imaging technologies, signal processing, machine learning, and computational image reconstruction methods
Obviousness Rationale
A person having ordinary skill in the art would recognize that the published technical disclosure represents predictable variations of the source patent's core DOT imaging methodology. The proposed enhancements of adaptive signal intensity adjustment and advanced computational processing techniques are logical extensions of the existing DOT imaging framework. These modifications represent standard engineering approaches to improving medical imaging resolution and diagnostic accuracy.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,289 |
|---|---|
| Title | Systems and methods of optimizing functional images of a lesion region using guided diffuse optical tomography |
| Assignee(s) | Washington University |